轮状病毒检测在儿童病毒性肠炎临床诊断中的价值及意义  

The clinical diagnostic value and significance of rotavirus detection in children's viral enteritis

作　　者：苗丽燕[1,2] 曲政海[1] 韩征利[2] 

机构地区：[1]青岛大学医学院附属医院,山东青岛266003 [2]山东省临淄区人民医院儿科

出　　处：《中国民康医学》2012年第15期1806-1808,共3页Medical Journal of Chinese People’s Health

摘　　要：目的:探讨轮状病毒检测在儿童病毒性肠炎临床诊断中的价值及意义。方法:应用胶体金方法对149例病毒性肠炎患儿粪便进行轮状病毒检测,并对其临床分型、治疗转归进行分析。结果:患病儿童年龄3个月至4岁1个月,平均年龄(13.9±9.6)月,149例患儿中,60例轮状病毒检测阳性,其中CK-MB升高23例(38.3%),ALT升高27例(45.0%);89例轮状病毒检测阴性,其中CK-MB升高18例(20.2%),ALT升高15例(16.9%),差异皆具有统计学意义(P<0.05)。在应用利巴韦林、热毒宁注射液治疗及对部分患儿加用丙种球蛋白,改用腹泻奶粉喂养后均获痊愈。结论:轮状病毒检测对于儿童病毒性肠炎临床分型及诊断有一定指导价值。Objective：To explore the clinical diagnostic value and significance of rotavirus detection in Children＇s viral enteritis. Methods：Stool samples from 149 infants with viral enteritis were detected by using the method of gold colloi, and to analyze the clinical classification and treatment outcome. Results： The age range of children with diarrhea were three months to forty - nine months , and the average age was （13.9 ＋- 9.6）months. Among 149 samples ,60 cases existed positive RV antigen,23 of which appeared the value rise of CK - MB（38.3% ） ,27 of which appeared that of ALT（45.0% ） ,89 cases existed negative RV antigen, 18 of which appeared the value rise of CK - MB（20.2% ） ,15 of which appeared that of ALT（ 16.9% ）. There were significant differences between both of them （P 〈 0. 05 ）. All the cases were recovered by the combination therapy of ribavirin and Retuning injection, part of which immunoglobulin （IvIg） and diarrhea milk was added. Conclusions： Rotavirus detection for clinical classification and diagnosis of children viral enteritis had a certain reference value and significance.

关 键 词：病毒性肠炎 临床特征 轮状病毒检测 治疗 

分 类 号：R512.5[医药卫生—内科学]