某院2011～2012年细菌耐药性监测  

Surveillance of bacterial resistance from the fifth people′s hospital of Chongqing from 2011-2012

作　　者：王华丽[1] 蒋洪彦[1] 赖富华[1] 

机构地区：[1]重庆市第五人民医院,400062

出　　处：《检验医学与临床》2012年第16期1999-2001,2003,共4页Laboratory Medicine and Clinic

摘　　要：目的了解该院2011～2012年临床常见病原菌对常用抗菌药物的耐药情况。方法使用法国生物梅里埃细菌分析仪行药敏鉴定和数据分析。结果共收集细菌967株,肠杆菌科细菌对碳青霉烯类、阿米卡星、哌拉西林/他唑巴坦的敏感性仍较高,敏感率在90%以上。大肠埃希菌和肺炎克雷伯菌属产ESBLs株阳性率分别为64.6%和28.8%。铜绿假单胞菌对亚胺培南、美罗培南、阿米卡星敏感率在90%以上,较其他医院的耐药率低。金黄色葡萄球菌对万古霉素和莫西沙星敏感率为90%以上;其耐甲氧西林株占22%,较其他医院低。粪肠球菌和屎肠球菌对万古霉素和利奈唑胺均高度敏感,未发现万古霉素耐药株。结论临床应合理选用抗菌药,及早检测耐药菌,加强感染控制是当务之急。Objective To investigate the resistant rates in the Fifth people＇s hospital of Chongqing from 2011 -2012. Methods VITEK2 system was used to detect and analyze. Results A total of 967 clinical isolates were col lected. The drug-resistant rates of Enterobacteriaceac in Imipenem, Meropenem, Amikacin and piperacillin/tazobactum were low,there were above 90%,149 strains of ESBLs-producing bacilli have been selected from Eseherichia coil and Klebsiella pneumoniae, the positive rates were 64.6% and 28.8%. Pseudomonas aeruginosa was sensitive to lmipen em,Meropenem and Amikacin. Compared with the other hospital the resistant rates, it was low. Staphylococcus aureus was sensitive to Vancomycin and Moxifloxacin. The detection rates of methicillin-resisitant Staphylococci were 22%. Enterococcus faecium and Enterococcus faecalis were sensitive to Vancomyein and Linezolid. None was resistant to vancomycin. Conclusion It is important to strengthen the surveillance of bacterial resistance to control the transmission of cloning strains in the hospital.

关 键 词：细菌耐药 抗菌药物 细菌药敏试验 

分 类 号：R195.1[医药卫生—卫生统计学]