62例非葡萄胎后妊娠滋养细胞肿瘤临床病例分析  

Explore the Non-mole Gestational Trophoblastic Tumor by Reviewing 62 Clinical Cases

作　　者：孙露亚[1] 钱建华[1] 

机构地区：[1]浙江大学医学院,杭州310006

出　　处：《浙江中医药大学学报》2012年第7期775-777,共3页Journal of Zhejiang Chinese Medical University

基　　金：国家自然科学基金批准项目(T20090718);浙江省自然科学基金资助项目(J20091445);浙江省重大科技专项和优先主题项目(I20100055)~~

摘　　要：[目的]通过62例非葡萄胎后妊娠滋养细胞肿瘤(GTT)临床病例分析,探讨非葡萄胎后GTT的临床特点、诊断方法,以期提高早期诊断水平。[方法]回顾性分析2005年3月至2009年3月间,浙江大学医学院附属妇产科医院收治的诊断为GTT患者247例中先期妊娠为非葡萄胎的GTT患者62例(25.1%)的临床资料,结合文献进行探讨。[结果]患者年龄以20～40岁为主,共49例(79.0%)。临床症状以阴道出血为主,共51例(82.3%)。诊断:根据病理诊断34例(54.8%);根据病史、血β-HCG、胸片、CT、超声等检查临床诊断28例,临床分期:Ⅰ期18例,Ⅱ期8例,Ⅲ期30例,Ⅳ期6例。[结论]非病理确诊的病例主要根据血β-HCG诊断,结合影像学检查可提高其早期诊断率,明确临床分期。[Objective] To explore the clinical features, diagnostic methods of non-mole gestational trophoblastic tumor by re＋ viewing 62 clinical cases whose previous pregnancies are non-mole, in order to improve the level of early diagnosis of the disease. [Methods] Clinical records of 62 patients, with gestational trophoblastic tumor whose previous pregnancies are non-mole, were reviewed. These patients were selected from the total 247 GTT patients, diagnosed by Women＇s Hospital, Medi- cal School of Zhejiang University from March 2005 to March 2009. Literature review was integrated into the discussion in this study.[Results] Majority of patients（49/62） were in the age of 20~40 years. The most common clinical symptom was vaginal bleeding, a total of 51 cases. Diagnosis： 34 patients were diagnosed by the pathological test;28 patients were di- agnosed by history of blood beta-HCG, chest X-ray, CT and ultrasound scanning. Clinical stages：I：18 cases, II：8 cases, III： 30 cases, IV： 6 cases. [Conclusion] Blood β-HCG and clinical imaging tests can improve early diagnosis rate for patients without pathological evidence, as well as are helpful for clinical stage.

关 键 词：非葡萄胎 GTT 病理 诊断 临床分期 

分 类 号：R714.43[医药卫生—妇产科学]