噻唑类化合物应用研究新进展  

Recent advances in application of thiazole compounds

作　　者：崔胜峰[1] 王艳[1] 吕敬松[1] DAMU Guri L.V. 周成合[1] 

机构地区：[1]西南大学化学化工学院,重庆400715 [2]Indian Institute of Chemical Technology(IICT),Hyderabad-500607,India

出　　处：《中国科学：化学》2012年第8期1105-1131,共27页SCIENTIA SINICA Chimica

基　　金：国家自然科学基金(21172181;外国青年学者研究基金81250110089);重庆市自然科学基金重点项目(CSTC2012jjB10026);高等学校博士学科点专项科研基金(博导类)(SRFDP20110182110007);中央高校基本科研业务费专项资金(XDJK2011D007;重点项目XDJK2012B026)资助

摘　　要：噻唑环是一类重要的含氮硫杂原子的五元芳杂环,其特殊的结构使得噻唑类化合物在化学、药学、生物学和材料科学等诸多领域具有广阔的应用前景,显示出巨大的开发价值,受到广泛关注.本文结合作者的研究工作,参考国内外近五年文献,系统地综述了噻唑类化合物在医药、农药、材料、生物染色剂和超分子化学领域应用研究进展.Thiazole ring is an important five-member aromatic heterocycle with nitrogen and sulfur atoms. This special structure of thiazole ring endows its derivatives to exhibit wide potential application in chemical, pharmaceutical, biological and material scicences and so on, which show great development value and attract increasingly special attention. A large number of researches have been focusing on thiazole compounds, the progress have been rapidly developing, and become one of highly active topics in recent years. Combining with authors＇ researches and referring to other works from literatures in recent five years, this work systematically reviewed the recent advances of the whole range of thiazole compounds in medicinal agents, agrochemicals, materials, biological stains and supramolecular chemistry.

关 键 词：噻唑抗菌/抗真菌/抗结核/抗癌/抗病毒/降血糖/ 消炎镇痛/抗癫痫/抗寄生虫/抗氧化杀虫剂/除草剂/杀菌剂染料生物染色剂抗腐蚀非线性光学材料电致发光阳离子受体/阴离子受体 

分 类 号：O626.25[理学—有机化学]