金属负载型阳离子树脂催化合成琥珀酸单乙酯  

Synthesis of Mono-Ethyl Succinate Catalyzed by Metal-loaded Cation Exchange Resin

作　　者：李运山[1] 

机构地区：[1]常州工程职业技术学院制药与生物工程技术系,江苏常州213164

出　　处：《化工技术与开发》2012年第8期7-10,共4页Technology & Development of Chemical Industry

摘　　要：采用金属负载型阳离子交换树脂作催化剂,乙醇和丁二酸酐为原料,对琥珀酸单乙酯的合成进行了研究,确定了最佳工艺条件:原料摩尔比n(乙醇)/n(丁二酸酐)=1.3:1,催化剂用量占丁二酸酐用量的15%,反应温度85℃,反应时间90min,乙酸正丁酯的产率达到93%以上。Mono-ethyl succinate was synthesized with ethanol and succinic anhydride catalyzed by metal-loaded cation exchange resin. The influence factors and the optimum process conditions were determined： mole ratio n（ethanol ）/n（succinic anhydride） =1.3 ： 1, metal-loaded cation exchange resin was 15% of the amount of succinic anhydride, temperature 85 ℃ and reaction time 90 minutes. Under these conditions, the yield of mono-ethyl succinate was above 93 %.

关 键 词：琥珀酸单乙酯 阳离子交换树脂 乙醇 丁二酸酐 最佳工艺条件 

分 类 号：TQ225.24[化学工程—有机化工]