急性扩容性血液稀释对渗透压和电解质的影响  

Change of osmosis pressure and electrolyte during hypervolemic hemodilution

作　　者：孙峰丽[1] 何颖[1] 王保国[1] 王恩真[1] 

机构地区：[1]首都医科大学附属北京天坛医院麻醉科,北京100050

出　　处：《山西医科大学学报》2000年第4期361-363,共3页Journal of Shanxi Medical University

摘　　要：目的　对比观察了乳酸钠林格液和佳乐施在术前急性扩容性血液稀释前后渗透压和电解质的变化。方法　 2 0例病人随机分为佳乐施组 (组 1)和乳酸钠林格液组 (组 2 ) ,病人入室开辟静脉后分别给予两组液体 10ml/kg ,30min输注完毕 ,分别于输液前后抽血查血常规 (RT)电解质和渗透压。结果　两组扩容前后MAP ,HR和渗透压 (OSM )无明显变化 ,血K+稀释性降低 ,分别下降 13 1%和 11 9%。组 1扩容后HCT下降明显 ,(4 0 1± 2 3至 31 6± 3 2 )下降了 2 0 9% ,血Na+明显增加(141 4± 8 2至 15 0 9± 8 4,P <0 0 5 ) ,但仍在正常范围之内。组 2扩容后HCT明显下降 (4 0 6± 3 3至 35 5± 3 8) ,下降了12 6 % ,血Na+在正常范围之内。结论　佳乐施扩容效果优于乳酸钠林格液但可致血Na+升高。Objective To compare the change of osmosis pressure and electrolyte during hypervolemic hemodilution by gelofusine (G) and lactated Ringer's solution (LG). Methods Twenty neurosurgical patients were randomly allocated into two groups, group G and group LR.The patients were infused with G or LR,10 ml/kg in 30 min respectively.The blood pressure,HR,HCT,HGB,platelet, blood osmosis pressure and electrolyte were measured before and after hypervolemic hemodilution,respectively. Results MAP, HR, OSM did not change significantly in two groups. K +decreased by 13.1% and 11.9%, HCT decreased by 20.9% and 12.6%,respectively in group G and LR after hemodilution, and Na + increased after infusion of G. Conclusion Gelofusine used for hypervolemic hemodilution is better than lactated Ringer's solution.

关 键 词：渗透压 电解质 急性扩容性血液稀释 佳乐施 

分 类 号：R619[医药卫生—外科学]