吴茱萸中的黄酮苷类化合物  

Flavonoid glycosides from dried and nearly ripe fruits of Evodia rutaecarpa

作　　者：胡传芹[1] 杨鑫宝[2,3] 杨秀伟[1] 刘建勋[2,3] 

机构地区：[1]北京大学天然药物及仿生药物国家重点实验室药学院天然药物学系,北京100191 [2]北京中医药大学,北京100029 [3]中国中医科学院西苑医院,北京100091

出　　处：《中国中药杂志》2012年第17期2571-2575,共5页China Journal of Chinese Materia Medica

基　　金：国家“十二五”科技支撑计划项目(2011BAI07B08)

摘　　要：目的:研究吴茱萸的化学成分。方法:应用溶剂法和色谱法分离纯化化合物,利用谱学技术鉴定化合物结构。结果:从吴茱萸70%乙醇溶液提取物的正丁醇萃取部分分离得到15个化合物,该文报道其中4个黄酮苷类化合物的结构,分别为香叶木素-7-O-β-D-吡喃葡萄糖苷(1),异鼠李素-3-O-芸香糖苷(2),香叶木苷(3)和柯伊利素-7-O-芸香糖苷(4)。结论:化合物1,3,4均为首次从吴茱萸中分离得到。Objective： To study the chemical constituents from the dried and nearly ripe fruits of Evodia （Euodia）rutaecarpa. Method： The compounds were separated and purified by solvent and chromatographic methods. Their structures were identified by spectroscopic techniques. Result： Fifteen compounds were separated from the normal butanol extracts of the 70% aqueous ethanol extract of the dried and nearly ripe fruits of E. rutaecarpa. Among of them, four compounds were reported in the essay and identified as diosmetin-7-O-β-D-glucopyranoside（1）, isorhamnetin-3-O-rutinoside（2）, diosmin（3） and chrysoeriol-7-O-rutinoside（4）. Conclusion： Compounds 1, 3and 4were separated from the dried and nearly ripe fruits of E. rutaecarpa for the first time.

关 键 词：吴茱萸 芸香科 黄酮苷 化学成分 

分 类 号：R284[医药卫生—中药学]