儿宝颗粒对小儿厌食症动物模型胃窦和血浆β-内啡肽的调节作用  

REGULATION ACTION OF ER' BAO GRANULES ON THE SERUM LEVEL OF β-ENDORPHIN (EP) IN ANTRUM PYLORICUM AND PLASMA OF ANIMAL MODEL OF CHILD ANOREXIA

作　　者：张月萍[1] 杜永平 隆红艳[2] 汪受传[2] 史健[1] 吴少华[1] 

机构地区：[1]第四军医大学西京医院,陕西西安710032 [2]南京中医药大学儿科疾病研究室,江苏南京210029

出　　处：《山东中医药大学学报》2000年第4期301-302,共2页Journal of Shandong University of Traditional Chinese Medicine

基　　金：国家自然科学基金资助课题!(No.39670896)

摘　　要：采用病因模拟法建立小儿厌食症动物模型，放免测定该模型血浆和胃窦部β－内啡肽含量，探讨运脾复方儿宝颗粒治疗小儿厌食症的机制。结果表明；模型动物血浆和胃窦部β－内啡肽的浓度明显降低，运脾复方能显著增加胃窦部和血浆中β－内啡肽的浓度。提示β－内啡肽在小儿厌食症发病中起一定作用，运脾复方可通过促进外周β－内啡肽的分泌，达到改善食欲的治疗效果。To study the effects of Er'bao granules on β-EP in the juvenile rat model with anorexia,the model was established by imitating the major cause of children anorexia,and the β-EP concentration in antrum pyloricum and plasma of animals were examined by radioimmunossay. Experimental results indicated that the β-EP concentration were low both in antrum pyloricum and plasma of the model,which could be cured by Er'boo granules. The results suggest that β-EP plays an important role in anorexia for child,and Er' bao granules was effective on child anorexia in the way of improving β-EP sectretion.

关 键 词：儿宝颗粒 厌食症 β-内啡症 中医药疗法 

分 类 号：R272.605[医药卫生—中医儿科学]