阿奇霉素在多壁碳纳米管修饰电极上的电化学行为及其测定  

Electrochemical behavior and determination of azithromycin at a multi-wall carbon nanotube modified electrode

作　　者：习霞[1] 明亮[1] 

机构地区：[1]南通大学化学化工学院,南通226007

出　　处：《分析试验室》2012年第9期89-92,共4页Chinese Journal of Analysis Laboratory

基　　金：南通大学自然科学项目(10Z015);南通市应用研究科技计划项目(K2006018)资助

摘　　要：运用循环伏安法与线性扫描伏安法研究了阿奇霉素在多壁碳纳米管修饰玻碳电极上的电化学行为,建立了一种直接测定阿奇霉素的电化学分析方法。结果表明,与裸玻碳电极相比,多壁碳纳米管修饰电极能显著提高阿奇霉素的氧化峰电流,阿奇霉素的电极过程完全不可逆,存在典型的吸附特性。在优化的实验条件下,氧化峰电流与阿奇霉素浓度在3.0×10-7～2.5×10-5 mol/L和2.5×10-5～5.0×10-4 mol/L范围内呈现良好的线性关系,检出限为1.0×10-7 mol/L。The electrochemical behavior of azithromycin at the multi-wall carbon nanotube （MWCNT） modified glassy carbon electrode （GCE） was investigated by cyclic voltammetry （CV） and linear sweep voltammetry （LSV）. The experimental parameters were optimized, and a direct electroanalytical method for the determination MWCNT modified GCE, in contrast to that at the bare GCE. The electrode process of azithromycin was totally irreversible and adsorption-controlled. Under the optimized experimental conditions, the oxidation peak current was proportional to the concentration of azithromycin in the ranges of 3.0 x 10 -7 ~ 2.5 x 10 5 mol/L and 2.5 ＊10-5 ~ 5.0 ＊ 10-4 mol/L with a detection limit of 1.0 ＊ 10 7 mol/L.

关 键 词：阿奇霉素 伏安测定 碳纳米管 化学修饰电极 

分 类 号：O657.1[理学—分析化学]