嗜酸粒细胞型鼻息肉患者血清特异性IgE检测的临床分析  

Serum allergen-specific IgE in patients with eosinophilic nasal polyps

作　　者：徐明[1] 赵枫[2] 沈安民[1] 周浩杰[3] 

机构地区：[1]宁波大学医学院附属医院耳鼻咽喉科,浙江宁波315020 [2]宁波大学医学院附属医院检验中心 [3]宁波大学医学院附属医院病理科

出　　处：《临床耳鼻咽喉头颈外科杂志》2012年第17期772-773,共2页Journal of Clinical Otorhinolaryngology Head And Neck Surgery

摘　　要：目的:探讨不同类型鼻息肉(NP)患者对吸入性变应原的超敏性及相关性。方法:将83例NP患者按息肉标本内嗜酸粒细胞(EOS)计数多少分为嗜酸粒细胞型鼻息肉(ENP)和非嗜酸粒细胞型鼻息肉(nENP),所有NP患者进行血清变应原特异性IgE(sIgE)检测及统计学分析。结果:ENP和nENP患者分别为27例(32.53%)、56例(67.47%),其血清变应原sIgE阳性者分别为16例(59.26%)、13例(23.21%),2种类型间比较差异有统计学意义(P<0.01);尘螨是NP组最常见的变应原。结论:常年性吸入性变应原与ENP患者有相关性。Objective：To investigate the relationship between airborne allergen and patients with nasal polyps （NP）. Method： Eighty -three cases of patients with NP were classified into the eosinophilic group（ENP） and non e- osinophilic group（nENP） in terms of the EOS count in NP specimen, all patients underwent specific-IgE test with standardized allergens and the results were analyzed. Result： The specific-IgE positive rate was 59. 26% in ENP group and 23.21% in the nENP group respectively（P〈0.01）, and the positive rate of ENP was statistical significance compared with nENP. The dust mite was the most prevalent airborne allergen in ENP group. Conclusion： The perennial airborne allergens may play a certain role in the etiology and pathogenesis of NP.

关 键 词：变应原 嗜酸粒细胞 变态反应 鼻息肉 

分 类 号：R765.25[医药卫生—耳鼻咽喉科]