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作 者:高云[1] 刘彤[1] 阴赪茜[1] 孙涛[1] 李志忠[1] 张京梅[1]
机构地区:[1]首都医科大学附属北京安贞医院心内科十五病房,北京100029
出 处:《中华急诊医学杂志》2012年第8期863-868,共6页Chinese Journal of Emergency Medicine
摘 要:目的探讨急诊非创伤急性胸痛患者30d死亡的危险因素,建立非创伤急性胸痛危险性评估方法。方法回顾性分析2008—2010年北京安贞医院心内科急诊以胸痛为主诉的532例患者的临床资料,将30d内死亡患者和存活患者的病史、症状体征及化验检查资料进行对照,确定其30d死亡的独立预测因素,建立非创伤急性胸痛危险性评估表。死亡组与存活组间计量资料的比较采用独立样本t检验,计数资料的比较采用x。检验。危险因素分析用多因素logistic回归分析。结果人选的急诊胸痛患者年龄为(55.7±12.7)岁,其中45例在30d内死亡,病死率为8.4%。高血压病史(OR:4.28;95%CI:1.59~11.55)、胸痛持续时间延长(OR:1.1;95%CI:1.05~1.15)、呼吸困难(OR:6.61;95%CI:2.40—18.10)、心率增快(OR:1.02;95%C1:1.00~1.04)、白细胞(OR:1.18;95%C1:1.06~1.31)、D二聚体增高(OR:1.002;95%CI:1.001~1.002)是患者30d死亡的独立预测因素,而用药物可缓解的胸痛(OR:0.15;95%CI:0.04~0.65),SaO,(OR:0.89;95%CI:0.83~0.98),HCT增高(OR:0.92;95%CI:0.86~0.99)可降低30d的死亡风险。死亡组和存活组相比,非创伤急性胸痛危险性评分较高(P〈0.01)。不同评分区间患者病死率差异具有统计学意义(P〈0.叭)。结论非创伤急性胸痛危险性评分可以快速、有效地判断急诊心内科胸痛患者的预后,评价其30d的死亡风险。Objective To investigate the independent risk factors of 30-day mortality of non - traumatic acute chest pain in emergency department so as to get non -traumatic acute chest pain risk score. Methods The clinical data of 532 patients with non -traumatic acute chest pain were reviewed. The independent risk factors of 30 - day mortality were identified after analysis of medical history, symptom and sign, laboratory findings by univariate analysis and logistic regression. Non - traumatic acute chest pain risk score was made as per the odds ratios of these risk factors. Results The average age of the patients was (55. 7 +12. 7 ) years, and 45 patients (8. 4%) died after 30 days. In patients with non -traumatic acute chest pain, history of hypertension (OR: 4. 28; 95% CI: 1. 59-11. 55), prolonged chest pain (OR: 1. 1; 95% Cl: 1. 05-1. 15), dyspnea (OR: 6. 61; 95%CI: 2. 40-18. 10) and tachycardia (OR: 1. 02; 95%CI: 1. 00-1. 04), highleucocytecount (OR: 1. 18;95%CI: 1. 06-1. 31)andD -Dimer (OR: 1. 002; 95% CI: 1. 001-1. 002) predicted 30 - day mortality independently, whereas chest pain reheved by medicine (OR: 0. 15; 95% CI: O. 04-0. 65), high blood oxygen saturation (Sa02) (OR: O. 89; 95%C1: 0. 83-0. 98)and normal hematocrit (OR: O. 92; 95%CI: 0. 86-0. 99) were good markers to predict optimistic prognosis. Non - traumatic acute chest pain risk score washigher in 30 - day dead group than those in survival group significantly (P 〈 O. O1 ), and mortality was significantly different between groups with various risk stratification ( P 〈 O. O1 ). Conclusions Clinical physician can predict 30 - day mortality and evaluate prognosis in patients with acute chest pain by using non -traumatic acute chest pain risk score quickly and effectively.
分 类 号:R541.4[医药卫生—心血管疾病]
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