双氯芬酸钠胶浆剂与复方氨基比林注射液治疗外科感染性高热的对比研究  

Comparative Study of Diclofenac Mucilage and Compound Amidopyrine Injection in Treating Surgical Infection with High Fever

作　　者：马元华[1] 刘加升[1] 孟昭旭[1] 张广鹏[1] 

机构地区：[1]江苏省沛县中医院,江苏沛县221600

出　　处：《河北医学》2012年第12期1689-1691,共3页Hebei Medicine

摘　　要：目的:对比观察双氯芬酸钠胶浆剂与复方氨基比林注射液治疗外科感染性高热的退热效果。方法:将120例外科感染患者随机分为双氯芬酸钠胶浆剂组和复方氨基比林注射液组,每组60例,观察对比两组用药后的退热效果。结果:双氯芬酸钠胶浆剂组退热作用优于复方氨基比林注射液组,总有效率分别为98%和77%(P<0.01),显效率分别为90%和65%(P<0.001)。用药1h后平均体温分别降至37.4℃和38.4℃(P<0.001)。双氯芬酸钠胶浆剂组退热持续时间为(16.5±2.3)h,优于复方氨基比林注射液组的(9.8±3.1)h(P<0.001)。结论:双氯芬酸钠胶浆剂退热快、作用强、持续时间长。Objective： To compare the effect of diclofenac mucilage and compound amidopyrine injec- tion in treating surgical infection with high fever. Methods： Data of 120 patients suffering from surgical in- fection with high fever were randomly divided into groups ：60 cases in mucilage group, and 60 cases in injection group, and the antipyretic effect were observed. Result： The antipyretic effect of mucilage group （ with an overall effective rate of 98% ）was better than that of injection group （77%）, with a P-value less than O. O1, and thereremarkably effective rates were 90% and 65% for the two groups, respectively, with s P-value less than 0.001. Their average body temperature lowered to 37.4 ~C and 38.4~C in two groups, respectively （P〈 0. 001 ）60 minutes after drug administration. The antipyretic effect could be sustained for（ 16.5＋2.3 } hours in the mucilage group,Longer than those in the injection group（9.8＋3.1 } hours, （ P〈0.001 }. Conclusion： The efficacy of diclofenac mucilage can effectieely reduce temperatory and maintain a long time.

关 键 词：双氯芬酸钠胶浆剂 复方氨基比林注射液 外科感染 高热 

分 类 号：R605[医药卫生—外科学]