六味地黄生物制剂多糖对果蝇寿命及繁殖力的影响  

Effect of Liuweidihuang decoction metabolized by photosynthetic bacteria(LW-PSB) polysaccharides on the lifespan and fertility in Drosophila melanogaster

作　　者：陈朋[1] 吴思[1] 李天河[1] 丘婷[1] 赵越[1] 

机构地区：[1]广东药学院中药学院,广东广州510006

出　　处：《广东药学院学报》2012年第4期427-429,共3页Academic Journal of Guangdong College of Pharmacy

基　　金：广东省自然科学基金重点项目(825022401000006)

摘　　要：目的研究六味地黄生物制剂多糖对果蝇寿命及繁殖力的影响。方法采用美国黑腹果蝇为实验材料,经口喂果蝇不同质量浓度(0.1%、0.3%、0.9%)的六味地黄生物制剂多糖提取物,以普通培养基作为空白对照,观察其对果蝇寿命和繁殖力的影响。结果各浓度的六味地黄生物制剂多糖能够延长雌性果蝇的半数死亡时间、最高寿命、平均寿命及延长雄性果蝇的最高寿命,且能增加果蝇子一代和子二代成虫数。结论六味地黄生物制剂多糖对果蝇具有良好的抗衰延寿作用并提高其生殖能力,提示六味地黄生物制剂多糖可能为该制剂抗衰老作用的物质基础之一。Objective To study the effect of Liuweidihuang decoction metabolized by photosynthetic bacteria（LW-PSB） polysaccharides on the lifespan and fertility in Drosophila melanogaster.Methods Drosophila melanogaster were fed with different concentrations of LW-PSB polysaccharides（0.1%,0.3% and 0.9%） and normal medium was used as a control group.The lifespan and fertility of Drosophila melanogaster were observed.Results LW-PSB polysaccharides prolonged female Drosophila average life,maximum life,half death time and male Drosophila maximum life.Importantly,LW-PSB polysaccharides also enhanced Drosophila productivity.Conclusion The effects of LW-PSB polysaccharides in prolongation of Drosophila melanogaster aging are satisfactory.

关 键 词：六味地黄生物制剂多糖 黑腹果蝇 寿命 繁殖力 

分 类 号：R285.5[医药卫生—中药学]