搭桥术治疗DeBakey Ⅲ型主动脉夹层的流固耦合数值模拟  

Fluid-structure interaction numerical simulation of bypassed DeBakey Ⅲ aortic dissection

作　　者：初博[1] 乔爱科[1] 

机构地区：[1]北京工业大学生命科学与生物工程学院,北京100124

出　　处：《医用生物力学》2012年第4期386-391,共6页Journal of Medical Biomechanics

基　　金：国家自然科学基金资助项目(10772010;10972016;81171107);北京市自然科学基金资助项目(3092004)

摘　　要：目的研究旁路搭桥转流术治疗DeBakey Ⅲ型主动脉夹层的力学机理,并探讨该术式的有效手术方案。方法构建升-腹搭桥和锁-腹搭桥前后通腔型式和盲腔型式的DeBakey Ⅲ型主动脉夹层个性化模型,利用计算流体力学的方法,在生理流动条件下进行流固耦合数值模拟。结果搭桥后假腔的血液流动速度、压力和血管壁位移分别平均下降38.86%、15.347 kPa和39.46%。结论搭桥手术是一种在特定情况下治疗DeBakey Ⅲ型主动脉夹层的有效手术方式,具有很好的临床应用前景。Objective To investigate the mechanical mechanism of bypass graft for the treatment of DeBakey III aortic dissection and explore the valid surgical planning.Methods Patient-specific models of DeBakey III aortic dissection,including the models of through lumen and blind lumen,before and after bypassing between ascending aorta and abdominal aorta,between left subclavian artery and abdominal aorta,were constructed,and then numerical simulations were performed using computational fluid dynamics（CFD） method under physiological flow conditions based on fluid-structure interaction（FSI）.Results Blood flow velocity,pressure,vessel wall displacement of the false lumen after bypass graft were reduced by 38.86%,15.347 kPa and 39.46% on average,respectively.Conclusions Bypass graft is an effective surgical method for the treatment of DeBakey III aortic dissection under specific conditions with good prospects in clinical application.

关 键 词：主动脉夹层 旁路搭桥术 数值模拟 压力 血流动力学 计算流体力学 

分 类 号：R318.01[医药卫生—生物医学工程]