汕头市338例孕产妇弓形体感染调查  

338 Cases of Maternal Toxoplasmosis Infection Survey in Shantou

作　　者：曾嫦[1] 黄宇泽[1] 林祥伟[1] 

机构地区：[1]广东省汕头市中心医院检验科,广东汕头515031

出　　处：《河北医学》2012年第11期1653-1655,共3页Hebei Medicine

摘　　要：目的:了解孕产妇感染弓形体(TOX)的情况。方法:采用检测血清中TOX特异性抗体的血清学方法,对338例孕产妇(其中220例为胎儿流产孕妇,118例为畸胎产妇),60例对照组(门诊健检孕妇)的血清进行了TOX-IgM和IgG抗体检测。结果:220例流产孕妇血清TOX-IgM抗体阳性33例,阳性率15.0%;IgG抗体阳性12例,阳性率5.5%(总阳性45例,阳性率20.5%)。畸胎产妇118例TOX-IgM阳性15例,阳性率12.7%;IgG阳性7例,阳性率5.9%(总阳性22例,阳性率10.6%)。60例对照组TOX-IgM阳性1例,阳性率1.7%。3组TOX-IgM阳性率比较分别为:孕妇组差异有非常显著性意义(X2=48.758 P<0.001)。产妇组差异有显著性意义(X2=5.931 P<0.05)。结论:TOX感染与部分孕妇流产、死胎、畸胎有关。Objective： To understand the maternal infection toxoplasmosis（TOX）.Method： Using serological methods to detect the TOX specific antibodies in serum of 338 cases of pregnant women（including 220 cases of fetal loss pregnant women,serum of 118 cases of fetal teratogenic maternal）,60 cases of control group（out-patient health check pregnant women） were detected TOX-IgM and IgG antibody.Result： 220 cases of abortion,maternal serum TOX-IgM antibody was positive in 33 cases,the positive rate was 15.0%;IgG antibody was positive in 12 cases,the positive rate was 5.5%（total 45 cases positive,the positive rate of 20.5%）.Teratogenic maternal 118 cases TOX-IgM was positive in 15 cases,the positive rate was 12.7%;of IgG was positive in seven cases,the positive rate of 5.9%（total 22 cases positive,the positive rate of 10.6%）.TOX-IgM positive one case in the control group,the positive rate was 1.7%.In TOX-IgM positive rate three groups are as follows： pregnant women group difference was significant（X2 = 48.758,P 0.001）.Maternal group difference was significant（X2 = 5.931,P 0.05）.Conclusion： TOX infection is related with the part of the miscarriage,stillbirth,birth defects.

关 键 词：孕妇流产 畸胎 弓形体感染 

分 类 号：R714.2[医药卫生—妇产科学]