球囊扩张联合微波介入治疗支气管结核的研究  

Interventional therapy of endobronchial tuberculosis with balloon dilatation and microwave

作　　者：黄义欢 陈伟生 陈晓兰 信丽红 

机构地区：[1]汕头市第三人民医院,广东汕头515073

出　　处：《中国热带医学》2012年第7期841-843,850,共4页China Tropical Medicine

摘　　要：目的观察球囊扩张联合微波和局部注药治疗支气管结核的有效性和安全性。方法106例支气管结核住院患者随机分成治疗组和对照组。治疗组应用球囊扩张联合微波和局部注药治疗,对照组予微波介入治疗,观察两组治疗效果。结果治疗组9个月后痰菌阴转率达到100%,胸片病灶有效率和电子支气管镜复查病变支气管总有效率93.2%,1年随访远期疗效为95.5%,明显高于对照组(P<0.05);FEV1由术前(1.3±0.7)L至(2.1±0.7)L,气促评分由术前2.2±0.7降为0.8±0.6(P<0.01),疗效较好,未见严重并发症。结论通过电子支气管镜球囊扩张联合微波和局部注药治疗支气管结核是一种安全、有效的方法。Objective To evaluate the efficacy and safety of balloon dilatation combined the interventional therapy with microwave and local drug-infusing for endobronchial tuberculosis.Methods The 106 inpatients with endobronchial tuberculosis were randomly divided into therapeutic group treated with balloon dilatation combined with interventional microwave plus local drug-infusing therapy and the control group treated with interventional microwave therapy.Results Nine months after treatment the sputum negative rate in patients of therapeutic group was 100 %.Both the improvement rate by X-ray and bronchoscopy were 93.2% and the one-year-follow-up prospective efficacy rate was 95.5%.All of which were higher than the controlled group（P〈0.05）.FEV1 increased from 1.3±0.7L and dyspnea index decreased from 2.2±0.7 to 0.8±0.6（P〈0.01）.No severe complications were found in these patients.Conclusions Bronchoscopy-assisted balloon dilatation in combination with microwave and local drug-infusing therapy is safe and effective for treatment of endobronchial tuberculosis.

关 键 词：球囊扩张 微波 支气管镜 支气管结核 

分 类 号：R523[医药卫生—内科学]