果酸产品治疗女性黄褐斑的疗效及安全性  

The efficacy and safety of glycolic acid in female melasma

作　　者：徐媛媛[1] 杨振海[1] 吴严[1] 徐天华[1] 耿龙[1] 高兴华[1] 陈洪铎[1] 李远宏[1] 

机构地区：[1]中国医科大学附属第一医院皮肤科,辽宁沈阳110001

出　　处：《中国美容医学》2012年第9期1544-1546,共3页Chinese Journal of Aesthetic Medicine

摘　　要：目的:观察果酸产品治疗女性黄褐斑的疗效及安全性。方法:用芯丝翠果酸产品治疗73名女性黄褐斑患者,包括果酸活肤治疗及日常治疗过程。活肤治疗过程每次持续3～5mi n,每3周1次,浓度从20%递增至35%,共5～10次。治疗前、后应用数码相机摄取面部照片,医生进行MASI评分、患者进行满意度评价。结果:经5次果酸活肤治疗及日常治疗,患者MASI评分从14.97下降至9.11,患者满意率为70%;经6～10次治疗后下降至8.77,患者满意率达到83%。果酸活肤治疗过程仅出现轻度刺痛、瘙痒、皮肤潮红等轻微不良反应,日常治疗过程未出现不良反应。结论:芯丝翠果酸产品能有效治疗女性面部黄褐斑,副作用轻微。Objective To observe the efficacy and safety of glycolic acid in female melasma.Methods Seventy-three female melasma patients were treated with glycolic acid,including chemical peeling treatment procedure and everyday treatment procedure.The former treatment lasted 3 to 5 minutes each time at an interval of 3 weeks at the concentration of 20% to 35% for 5 to 10 sessions.Photographs were taken with a digital camera pre-and post-treatments.Melasma area and severity index（MASI） score was assessed by dermatologists and the satisfaction was evaluated by patients themselves.Results After 5 sessions of chemical peeling treatment and everyday treatment,the MASI score decreased from 14.97 to 9.11 and the satisfactory rate was 70%.After 6～10 sessions treatments,the MASI score decreased to 8.77 and the satisfactory rate reached 83%.The chemical peeling procedure produced slight side effects including slight prick pain,itching and flush and no adverse effects were observed during the everyday treatment procedure.Conclusions Glycolic acid treatments were proved to be effective in the treatment of melasma with limited side-effects.

关 键 词：果酸 黄褐斑 美白 

分 类 号：R758.42[医药卫生—皮肤病学与性病学]