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作 者:李百惠[1,2] 王海俊[1] 马军[1] 吴双胜[3] 李珊珊[1]
机构地区:[1]北京大学公共卫生学院/儿童青少年卫生研究所,北京100191 [2]北京大学医学部主任办公室 [3]北京市疾病预防控制中心传染病地方病所
出 处:《现代预防医学》2012年第17期4384-4387,共4页Modern Preventive Medicine
基 金:科技部"十一五"国家科技支撑计划重点项目(2008BAI58B05);国家自然科学基金资助项目(30700668)
摘 要:目的探讨儿童肥胖与代谢综合征(MS)的关系,分析体重指数(BMI)和腰围与MS组分的关系。方法在北京市海淀区的8所学校选取1928名7~14岁小学生,测量其身高、体重和各MS组分,分析不同营养状况小学生MS组分的差异。采用多元线性回归和Logistic回归模型,分析BMI、腰围与MS组分的关系。结果除空腹血糖外,血压、血脂、腰围在不同营养状况小学生之间差异有统计学意义(P﹤0.05),表现为肥胖组﹥超重组﹥体重正常组。不同营养状况小学生高SBP、高TG、低HDL-C、中心性肥胖的检出率差异均有统计学意义(P﹤0.01),随BMI增加异常率增高。多元线性回归发现BMI和腰围均与除中心性肥胖外的其他MS组分有独立的相关性;除TC外,"腰围"对于其他MS组分的标化回归系数绝对值略大于"BMI"。除DBP外,对于其他MS组分,BMI与腰围同时升高(超重/肥胖且腰围≥P90)的OR值﹥BMI和腰围有且仅有一项偏高(超重/肥胖或腰围≥P90)﹥体重正常且腰围正常。结论儿童肥胖与代谢综合征关系密切,联合应用腰围和BMI有利于评估MS风险。OBJECTIVE To analyze the relationship of obesity and metabolic syndrome(MS)in children and study the role of BMI and waist circumference in predicting MS.METHODS Subjects were 1 928 students aged 7-14 years old from 8 primary schools in Haidian district,Beijing.Height,weight and components of MS were measured.MS components of children of different nutritional status were compared.The roles of BMI and waist circumference in predicting MS were analyzed by multiple linear regression and Logistic regression.RESULTS Except fasting plasma glucose,the blood pressure,lipids,waist circumference were significantly different among students of different nutritional status(P﹤0.05),obese﹥overweight﹥normal-weight.The abnormal rate of high SBP,high TG,low HDL-C and central obesity were significantly different among students of different nutritional status(P﹤0.01).As the results of multiple linear regression,BMI and waist circumference were independently associated with MS components except central obesity.The standardized regression coefficient of"waist"was greater than that of"BMI"for MS components except TC.For MS components except DBP,the OR of normal BMI and normal waist group was lower than OR of high BMI or waist group(overweight/obese or waist circumference≥P90),while the OR was the highest when both BMI and waist circumference were high(overweight/obese and waist circumference≥P90).CONCLUSION Childhood obesity is closely related to metabolic syndrome.Combined application of waist circumference and BMI in predicting MS risk is suggested.
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