孤立性肺结节恶性病变的危险因素分析  

Analysis on risk factors of malignant solitary pulmonary nodule

作　　者：阳世雄[1] 王斌强[1] 曾建业[1] 韦涌初[1] 黄思光[1] 

机构地区：[1]南宁市第二人民医院心胸外科,广西530031

出　　处：《中国临床新医学》2012年第8期707-710,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西科技开发项目(编号:桂科攻0816004-18)

摘　　要：目的探讨孤立性肺结节恶性病变的危险因素。方法统计120例孤立性肺结节的临床特征,对这些临床特征与孤立性肺结节的性质之间的关系作单因素分析,进一步对有统计学意义者作多因素分析。结果 120例中有64例(53.3%)术后病检结果为恶性病变。单因素分析中,吸烟史、结节大小、年龄及影像学表现4个因素差异具有统计学意义。多因素分析中年龄、影像学表现两个因素差异具有统计学意义。结论吸烟史、结节大小、年龄及影像学表现,尤其是后二者是孤立性肺结节恶性病变的危险因素,综合分析这些因素,可提高对孤立性肺结节良恶性判断的准确性。Objective To investigate the risk factor of malignant solitary pulmonary nodule （SPN）. Methods A monovariate analysis was used for exploring the correlation between clinical characteristics and pathological characteristics in 120 patients with SPN and then a multivariate analysis was performed in the factors with significant difference. Results Sixty-four patients postoperatively were proved to be malignant SPN. There was significant correlation between four factors （namely smoking, nodule size, age, image characteristics） and pathological characteristics in mon- ovariate analysis. However only two factors（ age and image characteristics）were left in multivariate analysis. Conclu- sion Smoking, nodule size, age and image characteristics, especially age and image characteristics, are the risk factors of malignant SPN. With a overall analysis for these factors, doctors can improve diagnosis accuracy of SPN.

关 键 词：孤立性肺结节 危险因素 诊断 

分 类 号：R563[医药卫生—呼吸系统]