绝经后骨质疏松症患者脂肪含量与骨密度的相关性研究  

Study of the correlation between fat content of postmenopausal osteoporosis patients and bone mineral density

作　　者：王广伟 霍力为 黄宏兴[2] 付丰平[3] 李泽钿[3] 

机构地区：[1]广东省广州市正骨医院,510045 [2]广州中医药大学附属骨伤科医院 [3]广州中医药大学2009级硕士研究生

出　　处：《国际中医中药杂志》2012年第9期782-784,共3页International Journal of Traditional Chinese Medicine

基　　金：广东省科技计划项目（项目编号：20098030801301）;广东省自然科学基金项目（项目编号：S2011010005671）

摘　　要：目的探讨绝经后骨质疏松症患者脂肪含量与骨密度的关系。方法选择自2010年10月至2011年1月广东省部分地区行骨密度检测诊断为骨质疏松症的144例女性患者，年龄为50-75岁。根据中医辨证分型分为肾阳虚衰组、肝肾阴虚组、脾肾阳虚组、气滞血瘀组。4组患者均行全身脂肪含量检测，所得数据采用SPSS16．0统计软件建立数据库进行统计分析。结果L卜4平均骨密度（BMD）比较，肾阳虚衰组最大、脾’肾阳虚组次之、气滞血瘀组、较小，四组之间比较均有统计学意义（P〈0．05）。脂肪含量比较，肾阳虚衰组脂肪含量较少，脾肾阳虚组次之，气滞血瘀组含量较多，肾阳虚衰组、肝肾阴虚组、脾肾阳虚组两两比较无统计学意义（P〉0．05）；三组分别与气滞血瘀组比较均有统计学意义（P〈0．05）；脂肪含量、L1～4平均BMD值呈负相关。结论4组中，气滞血瘀型的骨质疏松重于其他组；脂肪含量与骨密度呈负相关。Objective To explore the relationship between fat content ofpostmenopausal osteoporosis patients and bone mineral density （BMD） . Methods 144 female osteoporotic patients with the age of 50-75 years were choosen from gnangdong province from October 2010 to January 2011. According to TCM syndrome differentiations, these patients were divided into kidney Yang deficiency group, liver-kidney Yin deficiency group, spleen and kidney Yang deficiency group and Qi stagnancy and blood stasis group. Four groups of patients were performed total body fat content detection. The data were analyzed by software SPSS 16.0. Results Comparing of L1-4 average BMD in four groups showed： BMD of Kidney Yang deficiency group was maximum, followed by spleen and kidney Yang deficiency group, and the BMD of Qi stagnancy and blood stasis group was minimum. Comparison between the four groups showed statistical significance （P〈0.05） . Comparing of body fat content Iin the four groups showed： the body fat content in the kidney Yang deficiency group was minimum, followed by spleen and kidney Yang deficiency group, and body fat content in Qi stagnancy and blood stasis group was maximum. Pair-comparison in kidney Yang deficiency group, liver-kidney Yin deficiency group, spleen and kidney Yang deficiency group showed no statistical significance （P〉0.05） . While these three groups showed statistical difference when comparing with Qi stagnancy and blood stasis group （P〈 0.05） . The body fat content and L1-4 average BMD had negative correlation. Conclusion Osteoporosis in Qi stagnancy and blood stasis group was more serious than the other three other groups. Fat content was negatively related with bone density.

关 键 词：骨质疏松症 脂肪含量 骨密度 

分 类 号：R580[医药卫生—内分泌]