青海省麻疹疫苗强化免疫后出现疑似预防接种异常反应病例分析  

Analysis on the case features of adverse events following immunization after measles supplementary immunization activities in Qinghai

作　　者：贾有菊 

机构地区：[1]青海省疾病预防控制中心,西宁810007

出　　处：《医学动物防制》2012年第8期898-900,共3页Journal of Medical Pest Control

摘　　要：目的探讨我省麻疹强化免疫后发生的疑似预防接种异常反应(Adverse Events Following Immunization,AEFI)的病例特征,评估麻疹减毒活疫苗(Measles Attenuated Live Vaccine,MV)的安全性,为AEFI监测、诊断和处理提供科学依据。方法通过书面报告及全国AEFI监测网络报告系统,收集所有报告个案数据,采用描述性方法对相关指标进行分析。结果青海省麻疹疫苗强化后共报告AEFI病例65例,报告发生率为42.02/100万剂。大部分病例报告来自西宁,占58.46%;临床表现以发热伴全身皮疹、紫癜等过敏性反应为主,占56.92%。所有病例预后良好,无严重病例及死亡病例。结论麻疹疫苗的安全性好,预防接种服务质量良好。本省AEFI监测报告病例少,灵敏性较低。Objective To investigate the case features of AEFI after measles supplementary immunization activities in Qinghai,and evaluate the safety of MV,so as to provide scientific basis for AEFI monitoring,diagnosis and disposal.Method Collecting all the data of reported cases through written report and national AEFI surveillance system,and analyzing the relevant index through the descriptive methodology.Results 65 AEFI cases were reported after measles supplementary immunization activities in Qinghai,and the reported incidence rate was 42.02 per 1 million doses.58.46% of AEFI cases were reported from Xining City;and 56.92% had the same clinical symptoms,like fever,rash,purpura and other allergic reactions.The prognosis of all the cases were favorable,and no serious or death cases.Conclusions The safety of MV and the service quality of vaccination were good.In Qinghai Province,the reported cases of AEFI cases were few,and the sensitivity was low.

关 键 词：麻疹 强化免疫 疑似预防接种异常反应 

分 类 号：R186[医药卫生—流行病学] R511.1[医药卫生—公共卫生与预防医学]