复方内异宁联合针灸干预子宫腺肌病痛经的随机对照临床研究  

Combination of "Compound Neiyi'ning" with acupuncture for adenomyosis dysmenorrhea: A randomized controlled trial

作　　者：吴宁[1] 孟宝丽[1] 徐红[1] 徐芳[1] 戴明[1] 刘敛[1] 田丽霞[1] 唐虹[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032

出　　处：《上海中医药杂志》2012年第9期48-50,共3页Shanghai Journal of Traditional Chinese Medicine

基　　金：上海市卫生局科研项目(2009167)

摘　　要：目的观察中药复方内异宁联合针灸顺应月经周期节律干预子宫腺肌病的临床疗效,为临床治疗子宫腺肌病优化方案提供依据。方法采用随机对照的研究方法,将65例子宫肌腺病患者,随机分为针药组33例和中药组32例。两组均予复方内异宁顺应月经周期节律进行加减内服,针药组除服用中药外于经前7天至经行第2天联合针刺、艾灸治疗,观察两组疗程均为6个月;观察痛经程度、痛经强度(VAS视觉模拟)及痛经时间变化情况。结果治疗3个月、6个月后,针药组与中药组的PP集、ITT集临床总疗效比较,差异无统计学意义(P>0.05)。痛经程度、痛经强度、痛经时间两组治疗后均有明显改善(P<0.01),且针药组优于中药组。结论复方内异宁联合针灸能改善患者痛经程度与强度,缩短疼痛的时间,可作为子宫腺肌病的优化治疗方案。Objective To observe the clinical efficacy of ＂Compound Neiyi＇ ning＂ combined with acupuncture in the treatment of adenomyosis dysmenorrheal, and to supply optimum proposal in clinical treatment. Methods Sixty-five cases were randomized into two groups： 33 cases in acupuncture-medicine group and 32 cases in Chinese medicine group were treated by ＂Compound Neiyi＇ ning＂ orally, and the cases in acupuncture-medicine group were treated by acupuncture and moxibostion additionally 1 week before menstruation and at the second day during menstruation, witb the course of 6 months. The degree, intension and duration of dysmenorrhea were observed before and after treatment. Results After 3-month and 6-month treatment, no significant difference was found in clinical efficacy in PP and ITT in both of the groups （P 〉0.05）. After treatment, the degree, intension and duration of dysmenorrhea were improved significantly in both of the groups （ P 〈0. 01）, and the indexes in acupuncture-medicine group were better than that in Chinese medicine group. Conclusion ＂Compound Neiyi ＇ ning＇＂ can alleviate the degree, intension of dysmenorrheal, and shorten the duration of dysmenorrheal, which can be the optimmn proposal for the treatment of adenomyosis.

关 键 词：子宫腺肌病 痛经 针灸 复方内异宁 

分 类 号：R711.71[医药卫生—妇产科学] R246.3[医药卫生—临床医学]