炎性因子在自发性蛛网膜下隙出血后脑血管痉挛中作用的研究进展  

Advancement in Study on Inplammatory Factors Roles in Cerebral Vasospasm Following Spontaneous Subarachnoid Hemorrhage

作　　者：林冬[1] 朱占胜[1] 吴明灿[1] 

机构地区：[1]长江大学附属第一医院长江大学临床医学院,湖北荆州434000

出　　处：《医学综述》2012年第16期2560-2561,共2页Medical Recapitulate

摘　　要：脑血管痉挛(CVS)是自发性蛛网膜下隙出血(SAH)患者最终致残和死亡的主要原因。SAH后脑血管痉挛是一个复杂的多因素参与的病理生理过程。研究表明,炎症及免疫反应、氧化应激、细胞凋亡等在SAH后脑血管痉挛的发生、发展机制中有重要作用,而炎性反应及其炎性因子在上述各环节又发挥了基础及衔接的作用,现就此方面的相关研究进展综述如下。Cerebral vasospasm（CVS）is the major cause of disability and death to the patients of spontaneous subarachnoid hemorrhage（SAH）finally,CVS Following SAH is a kind of pathophysiological event involving multiple factors.Researches have showed that inflammation,immune,oxidative stress and apoptosis are closely relevant in the mechanism of genesis and development of CVS following SAH,while inflammation response and inflammatory factors play important basic and convergence roles,and here is to make a review on the research progress in above mentioned aspects.

关 键 词：炎性因子 自发性蛛网膜下隙出血 脑血管痉挛 

分 类 号：R651.15[医药卫生—外科学]