不同树龄厚朴生物活性成分的比较分析  

Comparison analysis of bioactive compounds of Mignolia officinalis Rehd. et Wils from different growth ages

作　　者：杨占南[1] 罗世琼[2] 余正文[1] 

机构地区：[1]贵州师范大学贵州省山地环境信息系统与生态环境保护重点实验室,贵州贵阳550001 [2]贵州师范大学生命科学学院,贵州贵阳550001

出　　处：《黑龙江医药》2012年第4期553-555,共3页Heilongjiang Medicine journal

基　　金：国家自然科学基金(No.31060056);贵州师范大学博士科研项目;贵州省中药现代化专项(黔科合中药字[2011]5046号);贵州省科技基金项目(黔科合J字[2011]2368号)

摘　　要：利用高效液相色谱法(HPLC)测定不同树龄厚朴中绿原酸、芦丁、金丝桃苷、槲皮苷、槲皮素、和厚朴酚和厚朴酚的含量。目的:为了比较分析同一来源不同树龄厚朴中7种活性物质含量变化,为最佳厚朴采集年龄提供参考。结果:绿原酸、金丝桃苷、槲皮素和厚朴酚在13年树龄时含量最高,分别达到0.28、0.033、0.018和5.90%;芦丁和槲皮苷在7年树龄时含量最高,其含量分别为0.34和0.52%;和厚朴酚和厚朴酚在10年树龄时其含量最高为2.40%。厚朴中的厚朴酚和和厚朴酚为主要成分在10年树龄和到26年树龄其成分的变化不大,10、13和26年树龄厚朴中7种活性物质总的含量分别为7.99、8.75和8.73%,总含量变化也不显著,因此,选10年的树为最佳厚朴采集年龄。Chlorogenic acid, rutin, hyperoside, quercitrin, quercetin, magnolol and honokiol in Mignolia officinalis Rehd. et Wils from different growth ages were analyzed by high performance liquid chromatography with photodiode- array detection （HPLC-DAD）. The aim is to compare change of 7 bioactive compounds of from different growth ages, this will be demonstrated to be very useful in optimal M. officinalis collected. The results showed that the contents of chlorogenic acid, hyperoside, quercitrin and magnolol, which were highest at 13 year, were 0.28、0.033、0.018 and 5.90%, respective. The contents of rutin and quercetin , which were highest at 7 year, were 0.43 and 0.52%, respective. The content of honokiol which were highest at 10 year, were 2.40%. The content of magnolol and honokiol of M. officinalis from 10 to 26 year were not remarkably variational. The all contents of 7 compounds, which were not remarkably variational, were 7.99、8.75 and 8.73%,respectively. So optimal M. officinalis collected was 10 year ages.

关 键 词：厚朴 树龄 活性成分 分析 

分 类 号：R927.2[医药卫生—药学]