不同HPV分型下阴道镜诊断宫颈病变94例分析  

Analysis on diagnosing cervical lesions with colposcope in 94 cases with different HPV types

作　　者：申明霞[1] 董志红[1] 赵淑华[2] 

机构地区：[1]新疆医科大学附属肿瘤医院妇科,新疆乌鲁木齐830011 [2]吉林大学第二医院妇产科

出　　处：《中国妇幼保健》2012年第26期4042-4045,共4页Maternal and Child Health Care of China

摘　　要：目的:探讨在HPV16(+)与其他高危型HPV(+)时电子阴道镜诊断不同级别宫颈病变的差异。方法:对94例可疑宫颈细胞学(TCT)异常的维吾尔族妇女行电子阴道镜检查,检查前采用核酸分子快速导流杂交基因分型技术进行HPV分型检测并行阴道镜下多点活检,比较在HPV16(+)与高危非HPV16(+)两组中电子阴道镜诊断不同级别宫颈病变的检出率。结果:电子阴道镜辨认HPV16(+)中的CINⅡ病变超过高危非HPV16(+)(P<0.05)。其中电子阴道镜诊断HPV16(+)的CINⅡ敏感性高于高危非HPV16(+)(P<0.01)。结论:电子阴道镜诊断HPV16(+)的CINⅡ及以上级别病变的敏感性高于高危非HPV16(+)。Objective： To explore the differences of cervical lesions of different grades diagnosed by colposcope in cases with posi- tive human papillomavirus （HPV） 16 and positive other high risk HPV types. Methods： Electronic colposcope examination was conducted in 94 Uighur women suspected of cervical cytological abnormality, before examination, HPV typing detection and multiple punch biopsy under colposcope were carried out with flow - through hybridization genotyping technique ; the detection rates of cervical lesions of different grades diagnosed by colposcope in positive HPV16 group and positive other high risk HPV types group were compared. Results： The detection rate of cervical intraepithelial neoplasia （CIN） ]] in positive HPV16 group was statistically significantly higher than that in positive other high risk HPV types group （P 〈 0. 05 ） ; the sensitivity of electronic colposcope for diagnosis of CIN lI in positive HPV16 group was statistically significantly higher than that in positive other high risk HPV types group （P 〈 0. 01 ） . Conclusion： The sensitivity of electronic colposcope for diagnosis of CIN 1I in cases with positive HPV16 was higher than that in cases with positive other high risk HPV types.

关 键 词：宫颈上皮内瘤变 电子阴道镜 人乳头瘤病毒 

分 类 号：R711.74[医药卫生—妇产科学]