32例宫颈妊娠治疗的临床分析  

Clinical analysis on treatment of 32 cases with cervical pregnancy

作　　者：秦海霞[1] 任艳芳[1] 杨君[1] 崔红凯[1] 杨瑞民[1] 

机构地区：[1]新乡医学院第一附属医院,河南卫辉453100

出　　处：《中国妇幼保健》2012年第26期4053-4055,共3页Maternal and Child Health Care of China

基　　金：河南省科技领军人才专项基金〔3049〕

摘　　要：目的:探讨两种宫颈妊娠保守性治疗的方法。方法:对1995年1月～2010年12月在新乡医学院第一附属医院就诊的32例宫颈妊娠患者的资料进行回顾性分析,32例患者中,1例行子宫全切术,31例选择保守性治疗,其中16例行子宫动脉栓塞化疗(Uterine arterial embolization chemotherapy,UAEC)后刮宫术,15例行甲氨蝶呤(MTX)保守治疗后刮宫。比较两组保守治疗患者的成功率、血β-HCG下降时间、平均住院时间及住院费用等。结果:UAEC+刮宫组的治疗成功率为100.0%,MTX+刮宫组的成功率为80.0%;UAEC+刮宫组的血β-HCG下降时间明显短于MTX+刮宫组(P=0.001);MTX+刮宫术组的住院时间明显高于UAEC+刮宫组(P=0.004);UAEC+刮宫组的平均住院费用高于MTX+刮宫术组(P=0.103)。结论:子宫动脉栓塞化疗(UAEC)后刮宫是一种安全有效的治疗宫颈妊娠的方法,该法出血少,成功率高,住院时间短。Objective： To explore two methods to treat cervical pregnancy conservatively. Methods： The data of 32 cases with cer- vical pregnancy who were admitted into the hospital from January 1995 to December 2010 were analyzed retrospectively, one case underwent total hysterectomy, and the other 31 cases chose conservative treatment, including 16 cases undergoing cervical curettage after uterine arterial embolization chemotherapy （UAEC） and 15 cases undergoing cervical curettage after conservative treatment with methotrexate （MTX） . The successful rates, the decrease times of blood [3 - human chorionic gonadotropin （ [3 - HCG） , the mean hospitalization times, and medical fees in the two groups were compared. Results： The successful rates in UAEC group and MTX group were 100. 0% and 80. 0% , respective- ly ; the decrease time of blood [3 - HCG in UAEC group was statistically significantly shorter than that in MTX group （ P = 0. 001 ） . The hos- pitalization time in MTX group was statistically significantly longer than that in UAEC group （ P = 0. 004） . The mean medical fee in UAEC group was higher than that in MTX group, but there was no statistically significant difference （P = 0. 103 ） . Conclusion： Cervical curettage after UAEC is a safe and effective method to treat cervical pregnancy, which has the advantages of less bleeding, higher successful rate, and shorter hospitalization time.

关 键 词：宫颈妊娠 保守性治疗 子宫动脉栓塞化疗 刮宫术 甲氨蝶呤 

分 类 号：R714.22[医药卫生—妇产科学]