裸鼠荷瘤实验中常见问题的解析和总结  

Summarize of the Common Problem and the Experience of Tumor-burdened in Nude-mice

作　　者：赵勇[1] 伍静[1] 毛峰峰[1] 赵善明[1] 张彩琴[1] 白冰[1] 师长宏[1] 

机构地区：[1]第四军医大学实验动物中心,西安710032

出　　处：《中国比较医学杂志》2012年第7期17-20,共4页Chinese Journal of Comparative Medicine

摘　　要：目的探讨裸鼠荷瘤过程中的出现的常见问题,提高裸鼠荷瘤的成功率。方法通过分析实验过程中影响裸鼠荷瘤的各种因素,寻求裸鼠荷瘤常见问题的解决方案。结果总结了在裸鼠荷瘤实验中的各种影响因素,并提出了合理的建议。结论裸鼠肿瘤模型的制备是研究肿瘤学、免疫学、药品与生物制品的安全性评价以及有效性筛选等研究课题的基础,本文为制备良好的裸小鼠肿瘤模型提供合理的建议。Objective Discussion the common problem of tumor-burdened in node-mice,In order to improve the success rate of tumor burden. Method Through analysis the influence of various factors of tumor-burden in node-mice, seek the solution of problem in tumor burdended. Result Summarized the various factors in the tumor burden, and put forward reasonable suggestions. Conclusion Node-mice tumor burden~ is the base of the oneology, drug and biological products of safety evaluation and effectiveness screening. This paper is to provide reasonable suggestions for the preparation of good nude mice tumor model.

关 键 词：裸鼠 肿瘤 模型 动物 

分 类 号：Q95-331[生物学—动物学] R332[医药卫生—人体生理学]