自制蛇伤中药对蝮蛇咬伤患者凝血功能的影响  

Effect of Self-made Chinese Medicine Treatment on Coagulation Function for Snakebite Patients with Agkistrodon halys Snakebites

作　　者：寇霄[1] 袁丞达[1] 罗维丹[1] 陶承军[1] 邬成霖[1] 

机构地区：[1]杭州市中医院,浙江杭州310007

出　　处：《中华中医药学刊》2012年第9期1998-2000,共3页Chinese Archives of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划资助项目(2008CB055);杭州市卫生科技计划资助项目(2011A051)

摘　　要：目的:观察蝮蛇咬伤患者凝血功能的变化情况和自制中药(外用蛇肿散及内服蛇毒消)对其的影响。方法:把93例蝮蛇咬伤患者,随机分为两个组,治疗组47例,对照组46例,均给予常规治疗,治疗组加服中药蛇毒消,均以7天为1个疗程。分别于治疗前及治疗后1天、3天、7天抽血观察并比较两组患者凝血功能指标(PT、TT、APTT、FIB、DD、PLT)的变化情况。结果:入院治疗前和治疗1天后两组凝血功能变化无明显差异性;治疗3天后,两组FIB、TT比较具有明显差异性(分别为P<0.05,P<0.05),其他指标两组比较无明显差异性;治疗7天后,两组指标FIB、TT比较具有明显差异性(分别为P<0.01,P<0.05),其他指标两组比较无明显差异性。结论:蝮蛇咬伤患者的凝血功能指标FIB、TT变化明显,中药能明显减轻蝮蛇咬伤患者凝血功能异常。Objective ： To observe of coagulation function in Agkistrodon halys snakebites and to analyze effect of self - made Chinese medicine treatment for snakebite on coagulation function in Agkistrodon halys snakebites. Methods ：93 pa- tients with Agkistrodon halys snakebite were randomly divided into two groups, 46 patients in the control group were trea-ted with conventional therapy and 47 patients in the trial group with conventional therapy and self - made Chinese medi- cine Treatment for snakebite. The changes of coagulation functions （ including IrF, TT, APT, FIB, DD and PLT） before treatment and 1,3,7 days later were compared between the two groups. Results ：The coagulation functions（ including PT, TT, APTF, FIB, DD and PLT）have no statistically significant difference between the two groups before treatment and 1 day later, but FIB and TT have statistically significant difference after 3,7 days treatment. Conclusion：The changes of FIB and TT are obvious in Agkistrodon halys snakebites and the abnormal coagulation function after Agkistrodon halys hired can improved by self- made Chinese medicine treatment.

关 键 词：自制蛇伤中药 蝮蛇咬伤 凝血功能 

分 类 号：R646[医药卫生—外科学]