单取代嘧啶基吡啶磺酰脲化合物的合成和生物活性  

Synthesis, Biological Activities of Mono-substituted Pyrimidine-pyridine Sulfonylurea Compounds

作　　者：童军[1] 郑占英[1] 李永红[1] 王素华[1] 李正名[1] 

机构地区：[1]南开大学元素有机化学国家重点实验室农药国家工程研究中心(天津),天津300071

出　　处：《农药》2012年第9期638-641,共4页Agrochemicals

基　　金："十二五"国家科技支撑计划科题(2011BAE06B05)资助

摘　　要：[方法]以单取代苯磺酰脲除草剂为基础,在分子中以吡啶环代替苯环设计合成了15个新的吡啶磺酰脲化合物,所有合成的化合物经核磁、元素分析确证,并对其生物活性进行了研究。[结论]剂量为300 g a.i./hm2时,大部分化合物对被测4种杂草的抑制活性不明显。[Methods] Based on the structure of mono-substituted pyrimidine sulfonylurea herbicides developed 15 novelpyridinyl sulfonylurea molecules containing mono-substituted pyrimidine rings were designed and synthesized. Thestructures of all compounds were confirmed by H NMR and elemental analysis. The bioassay was also carried out.[Conclusions] The biological screening results showed that the inhibitory effects of most of synthesized compounds werenot obvious at the concentration of 300 g a.i./ha.

关 键 词：磺酰脲 吡啶 合成 生物活性 

分 类 号：TQ457.2[化学工程—农药化工]