重视母乳中的一种新成分:microRNA  

A new component of breast milk:microRNA

作　　者：余章斌[1] 郭锡熔[1] 

机构地区：[1]南京医科大学附属南京妇幼保健院儿科,江苏南京210004

出　　处：《中国当代儿科杂志》2012年第9期719-722,F0003,共5页Chinese Journal of Contemporary Pediatrics

基　　金：国家自然科学基金资助项目(30973231);江苏省自然科学基金资助项目(BK2011107);江苏省医学创新团队项目(LJ201108)

摘　　要：MicroRNA(miRNA)是一类内源性非编码小分子RNA,存在于人类的多种体液中,近年来母乳中检测到多种miRNA,其中部分miRNA与婴儿免疫器官发育和免疫功能调节有关。本文阐述了母乳中microRNA的功能、临床循证证据及母乳与牛乳microRNA含量、种类的差异等。对母乳中新成分miRNA作用的解析,可以给儿童营养相关研究带来新的机遇,值得儿科营养学者的重视。MicroRNA（miRNA） is a class of non-coding endogenous small molecule single strand RNA which is found in human body fluids.In recent years,miRNAs have been found in breast milk and parts of miRNAs are related to immune organ development and regulation of the immune function in infants.This article summarizes the functions of miRNA in breast milk and evidence-based clinical practice,and the differences between microRNA content and species in breast milk and cow milk.Understandng the role of miRNA can bring new opportunities for childhood nutrition research.

关 键 词：母乳 成分 MICRORNA 儿童 

分 类 号：R174[医药卫生—妇幼卫生保健]