上海市金山地区乙型肝炎病毒感染危险因素分析  

Multivariate analysis on risk factors for hepatitis B virus infection

作　　者：欧强[1] 卢峪霞[1] 刘炳祥 王冯滨[3] 

机构地区：[1]上海市同济医院感染科,200065 [2]上海闸北区中心医院 [3]上海市公共卫生临床中心感染科

出　　处：《中华全科医师杂志》2012年第9期675-676,共2页Chinese Journal of General Practitioners

摘　　要：为探讨上海市金山区乙型肝炎病毒（HBV）感染的危险因素，我们以65例HBsAg阳性者为研究对象，采用1：2病例对照研究，对照组130例，均为HBV血清学阴性的患者。单因素分析发现HBV感染的危险因素有乙肝家族史、口腔诊疗史、无乙肝疫苗接种史。进一步多因素分析显示乙肝家族史（OR=1．91）、无乙肝疫苗接种史（OR=0．49）和口腔诊疗史（OR=2．06）是HBV感染的独立危险因素。加强乙肝疫苗接种和乙肝防治知识的健康宣教，改变不良生活习惯，规范口腔诊所诊疗行为是降低本地区乙肝感染率的重要措施。To explore the major risk factors for hepatitis B （HBV） in Shanghai Jinshan district. A one-to-two matched case control study was performed among the residents of Shanghai Jinshan district in 2010. The data were analyzed by single factor and multivariate analysis performed with SAS 9. 13. Single factor analysis showed that the risk factors for hepatitis B were family member with hepatitis B, no vaccination history of hepatitis B virus vaccine and oral treatment. Muhivariable analysis showed that family member with hepatitis B （ OR = 1.91 ）, no vaccination history of HBV vaccine （ OR = 0. 49 ） and oral treatment （OR = 2. 06 ） were independent risk factors for HBV infection in Shanghai Jinshan district. Strengthening health education for HBV prevention, modifying unhealthy living habits and standardizing the treatment of oral diseases are important measures for lowering infectious rate of HBV.

关 键 词：肝炎病毒 乙型 危险因素 

分 类 号：R51[医药卫生—内科学]