炎症与糖尿病肾病  

Inflammation and diabetic nephropathy

作　　者：鲍溪荷[1] 叶山东[1] 

机构地区：[1]安徽医科大学附属安徽省立医院内分泌科,合肥230001

出　　处：《国际病理科学与临床杂志》2012年第4期325-329,共5页Journal of International Pathology and Clinical Medicine

基　　金：安徽省自然科学基金(11040606M159);安徽高校省级自然科学研究项目(KJ2011A157)~~

摘　　要：近年来,炎症反应在糖尿病及其并发症发病机制中的作用引起了人们的广泛关注,研究报道炎症因子及促炎症因子与糖尿病肾病的发生和发展密切相关,并认为糖尿病肾病是一种炎症性疾病,炎症因子的大量产生参与并促进糖尿病肾病的进展。本文重点就炎症因子与糖尿病肾病的关系以及抗炎治疗对糖尿病肾的保护作用进行综述。In recent years,inflammatory response in the mechanism of diabetes and its complications have received close attention.Many studies on inflammatory cytokines and factors that promote inflammation are closely related to the occurrence of diabetic nephropathy,and,conversely,diabetic nephropathy is regarded as a kind of inflammatory disease.The over-production of inflammatory cytokines in vivo and,specially in renal tissue,are involved in and promote the progress of diabetic nephropathy.This article reviews the relationship between these inflammatory factors and the diabetic nephropathy,and the protection that anti-inflammatory treatment offers the diabetic kidney.

关 键 词：糖尿病肾病 炎性反应 治疗 

分 类 号：R587.2[医药卫生—内分泌]