佛山市妊娠期妇女血清总胆汁酸水平的观察与分析  

Observation and analysis of the serum total bile acid level of pregnancy women in Foshan

作　　者：麦爱芬[1] 陈社安[1] 

机构地区：[1]广东省佛山市第一人民医院,广东佛山528000

出　　处：《中外医疗》2012年第23期18-18,20,共2页China & Foreign Medical Treatment

摘　　要：目的探讨佛山市不同孕期妊娠妇女血清总胆汁酸(TBA)在正常妊娠过程中的变化规律。方法用酶法检测孕妇血清中的TBA水平。结果早孕较非妊娠组相比差异无统计学意义(P>0.05),中孕和晚孕组的孕妇血清中TBA水平分别较非妊娠组相比差异有统计学意义(P<0.01),而且晚孕组与中孕组相比血清TBA水平也有明显升高,两者相比差异有统计学意义(P<0.01)。结论血清TBA在妊娠过程中持续升高,孕妇在妊娠时就有潜在发生妊娠性肝内胆汁瘀积症(ICP)的危险。Objective The city of Foshan different pregnancy pregnant women serum total bile acid（TBA）in normal pregnancy in the process of change.Methods Enzyme assay for the detection of maternal serum TBA level.Results Early pregnancy than nonpregnant group was no significant difference（P〉0.05）in pregnancy and pregnant group in maternal serum TBA level were compared with nonpregnant group compared the difference was statistically significant（P〈0.01）,and pregnant group and in pregnant group compared with the serum levels of TBA also had significantly higher,compared the difference was statistically significant（P〈0.01）.Conclusion The serum levels of TBA during pregnancy continues to rise,women in pregnancy when there is a potential pregnancy intrahepatic cholestasis（ICP）risk.

关 键 词：总胆汁酸 妊娠 肝内胆汁瘀积症 

分 类 号：R714.25[医药卫生—妇产科学]