坎地沙坦酯片对正常高值血压患者的疗效观察  

Investigation of curative effeet of the Candesartan cilexetil tablets to the patients with high normal blood pressure

作　　者：丁大植[1] 尤昕[2] 方恩男[1] 朴美娜[1] 关立克[1] 

机构地区：[1]延边大学附属医院心血管内科,吉林延吉133000 [2]延边大学附属医院检验科,吉林延吉133000

出　　处：《吉林医学》2012年第25期5393-5394,共2页Jilin Medical Journal

基　　金：国家自然科学基金资助项目(项目编号:30760240)

摘　　要：目的:观察坎地沙坦酯片对伴有头晕、头痛的正常高值血压患者的影响。方法:选择伴有头晕、头痛的正常高值血压患者86例,随机分为对照组和治疗组。对照组非药物治疗,治疗组非药物治疗加坎地沙坦酯片。结果:①临床疗效:总有效率对照组32.6%,治疗组88.4%,治疗组明显优于对照组(P<0.01)。②血压变化:两组治疗后与同组治疗前比较,对照组收缩压(SBP)和舒张压(DBP)有所降低,但差异无统计学意义(均P>0.05);而治疗组SBP和DBP明显降低(均P<0.01)。两组治疗后相比较,治疗组SBP和DBP明显降低(均P<0.01)。结论:坎地沙坦酯片治疗伴有头晕、头痛症状的正常高值血压者有效、安全。Objective To investigate the curative effect of Candesartan eilexetil tablets in the patients who have dizziness ,headache and high normal blood pressure. Method Eighty -six patients with dizziness, headache and high normal blood pressure were divided into two groups;one was control group,the other was treatment group. The control group received non -drug therapy, the treatment group received non -drug therapy added Candesartan cilexetil tablets. Results （1） Clinical curative effect：the total effective rate of the treatment group （88.4%） was obviously higher than that of the control group （32. 6% ） （P 〈 0. 01 ）. （2） The changes of blood pressure：after treatment, the SBP （systolic blood pressure,SBP） and DBP （Diastolic blood pressure,DBP） decreased in control group and had no statistically signifi- cant （P 〉 0. 05） but decreased notably in treatment group （P 〈 0. O1 ）. Then compared the two groups after therapy, the SBP and DBP of treatment group decreased more than control group （ P 〈 0. 01 ）. Conclusion The compound treatment of Candesartan Cilexetil Tablets has utility and safety effect for the patients with dizziness, headache and high normal blood pressure.

关 键 词：正常高值血压 头晕、头痛 坎地沙坦酯片 

分 类 号：R544.1[医药卫生—心血管疾病]