Leucyl-tRNA synthetase： double duty in amino acid sensing  

作　　者：Raúl Durán Michael N Hall 

机构地区：[1]Biozentrum, University of Basel, Klingelbergstrasse 50/70, CH-4056 Basel, Switzerland

出　　处：《Cell Research》2012年第9期1312-1314,共3页细胞研究（英文版）

摘　　要：The cellular response to amino acids is controlled at the molecular level by TORC1. While many of the elements that participate in TORC1 signaling are known, we still have no clear idea how cells sense amino acids. Two recent studies found that leucyltRNA synthetase （LRS） is a leucine sensor for TORC1, in both yeast and mammalian cells.

关 键 词：亮氨酰-TRNA合成酶 氨基酸 检测 哺乳动物细胞 细胞反应 分子水平 亮氨酸 LRS 

分 类 号：Q55[生物学—生物化学] Q517