搔刮术对子宫内膜形态不良患者体外受精-胚胎移植临床结局的影响  

Effects of curettage on the clinical outcomes of in vitro fertilization and embryo transfer of irregular echo endometrium

作　　者：葛明晓[1] 张金玉[1] 李海霞[1] 徐琳[1] 袁启龙[1] 

机构地区：[1]广州军区广州总医院妇产科生殖医学中心,510010

出　　处：《中国妇产科临床杂志》2012年第5期352-354,共3页Chinese Journal of Clinical Obstetrics and Gynecology

摘　　要：目的探讨搔刮术对子宫内膜形态不良患者IVF-ET周期临床结局的影响。方法 IVF-ET前自然周期阴式超声监测子宫内膜,卵泡晚期子宫内膜非三线征者共77例,随机分组:观察组(47例)在垂体降调节超促排卵周期月经第1～2天行子宫内膜搔刮术;对照组(30例)不做处理。比较两组患者的一般临床资料及治疗结局。结果两组的年龄、不孕因素及年限、用药量、移植胚胎数等比较差异无统计学意义(P>0.05),观察组的种植率(30.30%)及临床妊娠率(53.19%)显著高于对照组(分别为15.15%和30%)。观察组85.11%的患者搔刮术后卵泡晚期超声下子宫内膜形态得到改善。结论子宫内膜搔刮术能改善子宫内膜形态,提高周期临床妊娠率。Objective To explore the effect of curettage on the clinical outcomes of irregular echo endometri um of natural cycle late follicular phase in IVF- ET cycles. Methods Before IVF- ET cycle, endometrial thickness were monitored by transvaginal ultrasound, which were performed in late follicular phase in all patients. There were 77 patients with abnormal endometrial echoes in late follicular phase of natural cycle. All the patients were divided into observation group （n=47） and control group （n=30） randomly. Curettage was performed on day 1-2 of men- strual cycle in IVF - ET cycle in the observation group, while it was not performed in the control group. The clinical outcomes and endometrial thickness and morphologic pattern were compared between the two groups. Results The rates of embryo implantation, clinical pregnancy in the observation group were 30.30 % and 53.19%, which were significantly higher than those in the control group （15.15% and 30%）. Endometrial echogenic pattern was amelio- rated in late follicular phase in 85.11%0 of patients in observation group. Conclusion Curettage could not only sig- nificantly ameliorate the echogenic pattern of endometrium, but also improve the implantation and clinical pregnancy rates of IVF- ET.

关 键 词：内膜搔刮 体外受精-胚胎移植 子宫内膜形态 妊娠率 

分 类 号：R714.8[医药卫生—妇产科学]