垂体后叶素在腹腔镜下大子宫切除术中的应用  

Effect of Pituitrin in Laparoscopic Hysterectomy for Large Uterus

作　　者：梁静[1] 吴丽杰[1] 王扬[1] 

机构地区：[1]中日友好医院妇产科,北京100029

出　　处：《中国微创外科杂志》2012年第9期799-801,共3页Chinese Journal of Minimally Invasive Surgery

摘　　要：目的探讨垂体后叶素在腹腔镜下大子宫切除术中的应用价值。方法对2011年1～7月26例子宫如孕12～16周者(大子宫组)和36例子宫小于10周者(非大子宫组)行腹腔镜全子宫切除术。大子宫组术中给予垂体后叶素6 U局部注射,非大子宫组常规手术。比较2组手术时间、术中出血量、血压和心率变化及术后并发症等情况。结果大子宫组子宫切除时间较非大子宫组长8 min[(33.3±8.7)min vs.(25.2±7.6)min,t=3.888,P=0.000],7例术中血压升高幅度超过30%,经处理后很快恢复。2组子宫切除的出血量差异无显著性,术中、术后均未发生并发症。结论腹腔镜大子宫切除术中使用垂体后叶素局部注射安全、有效,术中出血、手术时间、并发症与非大子宫手术相近。Objective To evaluate the effect of pituitrin in laparoscopic hysterectomy （LH） for patients with large uterus. Methods From January to July 2011, we performed LH on 62 patients. The patients was divided into large uterus group （26 cases, uterine size 12- 16 weeks gestation） and non-large uterus group （36 cases, uterine size 〈 10 weeks gestation）. The large uterus group received pituitrin （6 U） injection intraoperatively, while the non-large uterus group underwent routine LH only. The operation time, intraoperative blood loss, blood pressure, heart rate, and postoperative complications were compared between the two groups. Results The mean operation time of the large-uterus group was significantly longer than that of the non-large uterus group by 8 minutes [（33.3 ±8.7） min vs. （25.2±7.6）min, t=3.888, P=0. 000]; seven cases from the large-uterus group had the blood pressure increased by 30% during the operation, but was controlled quickly. No significant difference was found in the intraoperative blood loss, and intra- and postoperative complications between the groups. Conclusions LH for large uterus with pituitrin is safe and effective, and is similar to a routine LH in terms of intraoperative blood loss, operation time and rate of complications.

关 键 词：腹腔镜 大子宫 垂体后叶素 子宫切除术 

分 类 号：R713.42[医药卫生—妇产科学]