体外观察自动脉冲射频模式下设定不同温度时组织相关参数的变化  

THE CHANGES OF TISSUE CORReLATED PARAMETERS UNDER DIFFERENT TEMPERA-TURE IN AUTOMATIC PULSED RADIOFREQUENCY MODE

作　　者：罗芳[1] 于晓彤[2] 李多依[1] 黄佑庆[3] 吴大胜[4] 崔健君[5] 刘延青[1] 樊碧发[6] 

机构地区：[1]首都医科大学附属北京天坛医院疼痛中心,北京100050 [2]上海理工大学医疗器械与食品学院,上海200093 [3]昆明医学院附属第二医院疼痛科,昆明650101 [4]吉林省人民医院疼痛科,长春130021 [5]中国医科大学盛京医院疼痛科,沈阳110004 [6]中日友好医院疼痛科,北京100029

出　　处：《中国疼痛医学杂志》2012年第9期544-547,共4页Chinese Journal of Pain Medicine

摘　　要：目的:观察自动脉冲射频模式下设定不同温度时组织相关参数的变化。方法:用Baylis疼痛射频治疗仪自动脉冲射频模式下分别设定脉冲射频温度为42℃、44℃、46℃、48℃、50℃、52℃、55℃、60℃、70℃、80℃和90℃,在37℃恒温水浴箱内进行新鲜蛋清实验。记录不同温度下治疗前、治疗后30 s、60 s、90 s、120 s、180 s、300 s和停止治疗后1 min时组织实际温度、电压和电阻。结果:50℃以下,随着脉冲射频设定温度的升高,组织达到设定温度、脉冲电压显著升高(P<0.01)、电阻轻微下降(P<0.01);50℃以上,即使增加脉冲射频的设定温度,组织的实际温度不再升高、脉冲电压也不增加、电阻较50℃时无显著性变化。各温度组均未观察到肉眼可见的热凝物。结论:Baylis疼痛射频治疗仪自动脉冲射频模式下升温至50℃可增加脉冲电场强度、无组织变性,可能具有临床应用前景。Objective： To observe the changes of tissue correlated parameters during the different temperat- ure in automatic pulsed radiofrequency mode. Methods： The temperature was settled on 42 ℃ , 44 ℃, 46 ℃,48 ℃,50 ℃, 52 ℃, 55 ℃, 60 ℃,70 ℃,80 ℃ and 90 ℃ respectively under automatic pulsed radiofrequency mode by Baylis pain radiofrequency instrument. The fresh egg white experiment was performed in 37 ＊（3 thermostatic water bath think. The changes of actual tissue temperature, voltage, and electric resistance before treatment, 30 s, 60 s, 90 s, 120 s, 180 s and 300 s after pulsed radiofrequency and 1 min after the cessation of pulsed radiofrequency were recorded. Results： The voltage significantly increased （P 〈 0.01） and the electric resistance slightly decreased （P 〈 0.01） with the increasing of settled temperature under 50＊（3 pulsed radiofrequency. However, compared with 50~（3 pulsed radiofrequency, no significant difference of voltage and electric resistance were observed in more than 50＊（3 groups. No macr- oscopic thermoset was observed in each group. Conclusion： 50℃ pulsed radiofrequency with increased ou- tput voltage without tissue denaturation under automatic pulsed radiofrequency mode of Baylis pain man- agement generator, possibly has a clinical application prospect.

关 键 词：脉冲射频 蛋清实验 电压 治疗 

分 类 号：R402[医药卫生—临床医学]