固定床催化4-苯基丁酸分子内酰化反应合成α-四氢萘酮  

Synthesis of α-Tetralone by Intramolecular Acylation of 4-Phenylbutyric Acid in a Fixed Bed Reactor

作　　者：卞妮妮[1] 毛建新[1] 赵晓倩[1] 丁龙华[1] 郑小明[1] 

机构地区：[1]浙江省应用化学重点实验室浙江大学催化研究所,浙江杭州310007

出　　处：《化学反应工程与工艺》2012年第2期180-183,共4页Chemical Reaction Engineering and Technology

基　　金：浙江省功能化多孔材料和绿色替代技术创新团队项目(2012R10014-04)

摘　　要：在固定床连续流动条件下,以4-苯基丁酸为原料,经分子内酰化反应合成α-四氢萘酮,考察了不同催化剂,反应温度和焙烧温度对催化剂性能的影响。结果表明,在900℃焙烧处理后的H-Beta分子筛对该反应具有较好的催化活性和稳定性,在220℃连续反应10 h,4-苯基丁酸的平均转化率达98.0%,α-四氢萘酮的平均得率为81.2%。The effect of different catalysts, reaction temperature and calcination temperature on the performance of the catalyst for synthesis of a-tetralone by intramolecular acylation of 4-phenylbutyric acids in fixed bed were investigated. The results showed that H-Beta zeolite which was calcined at 900 ℃ exhibited high activity and stability in the reaction. The average conversion of 4-phenylbutyric acid was 98.0% and the average yield of 6t-tetralone was 81.2% after reaction l 0 h at 220 ℃.

关 键 词：4-苯基丁酸 α-四氢萘酮 H-Beta分子筛 分子内酰化反应 

分 类 号：TQ426.6[化学工程] TQ612.3