椎间盘突出症CT诊断的荟萃分析  

Meta-analysis on CT diagnosis for intervertebral disc herniation

作　　者：王文轩[1] 杨汉丰[1,2] 李杨[1] 赵鹏[1] 高燕[1] 古健炜[1] 袁尉峰[1] 赵锐[1] 尹平[1] 任东梅[1] 

机构地区：[1]川北医学院附属医院放射科,四川南充637000 [2]医学影像四川省重点实验室,四川南充637000

出　　处：《现代医药卫生》2012年第17期2585-2586,2588,共3页Journal of Modern Medicine & Health

摘　　要：目的用荟萃（Meta）分析定量评价椎间盘突出症的CT诊断价值。方法检索Pubmed、OVID、EBSCO外文数据库、中国期刊全文数据库（CNKI）、中国生物医学文献数据库（CBM）和万方数据库中的相关文献,结合Cochrane协作网推荐内容制定纳入标准筛选文献,提取纳入研究的特征信息并对纳入文献进行质量评估。采用STATA 11.0、Meta-Disc 1.4软件进行统计学分析：检验异质性;计算汇总灵敏度、特异度及95%可信区间;计算汇总受试者工作特性曲线（SROC）下面积。结果纳入文献10篇,共含病例811例（1 051个椎间盘）。汇总灵敏度、特异度及其各自95%可信区间分别为0.73（0.69~0.76）、0.84（0.81~0.87）。加权SROC曲线下面积为0.839 4。结论对于椎间盘突出症的诊断,CT具有较高的特异度和准确率,可作为椎间盘突出症重要的临床筛查和诊断方法之一。Objective To assess the value of CT in diagnosis of intervertebral disc herniation with Meta analysis.Methods The retrieval in PubMed,OVID,EBSCO,CNKI,CBM and Wanfang data bases was performed to identify relevant English and Chinese language articles,respectively.The criteria for inclusion were established based on validity criteria for diagnostic research published by the Cochrane Methods Group on Screening and Diagnostic.The sensitivity,specificity,summary receiver operating characteristic（SROC） curves,area under the curve（AUC） and the heterogeneity were calculated with software of STATA 11.0 and Meta-Disc 1.4.Results Ten of 5 864 retrieved articles were included,with a total of 811 patients（1 051 disks）.The pooled weighted sensitivity and specificity for CT with 95% confidence interval（95%CI） after correction for standard error were 0.73（0.69-0.76） and 0.84（0.81-0.87）,respectively.The AUC of SROC was 0.839 4.Conclusion X-ray computed tomography has higher specificity and higher accuracy in diagnosing intervertebral disc herniationand and can be used as one of important clinical screening and diagnostic methods.

关 键 词：体层摄影术 X线计算机 腰椎/放射摄影术 椎间盘移位/放射摄影术 Meta分析 椎间盘突出 

分 类 号：R681.53[医药卫生—骨科学]