MR410与MR850湿化系统对有创机械通气患者湿化效果的比较  

Humidification Effect of MR410 Humidification System and MR850 Humidification System on Patients with Invasive Mechanical Ventilation:A Comparative Study

作　　者：谭伟[1] 代冰[1] 孙龙凤[1] 赵洪文[1] 康健[1] 

机构地区：[1]中国医科大学附属第一医院呼吸疾病研究所内科ICU,辽宁沈阳110001

出　　处：《中国呼吸与危重监护杂志》2012年第5期470-474,共5页Chinese Journal of Respiratory and Critical Care Medicine

基　　金：辽宁省医学高峰建设工程重点科研项目(编号:200922)

摘　　要：目的比较MR410与MR850湿化系统在机械通气治疗患者中的湿化效果。方法分析69例经气管插管或气管切开机械通气患者,随机分为MR850组和MR410组。测量两组患者气管插管处或气管切开处的温度和相对湿度,计算绝对湿度;评价湿化初始3 d痰液黏稠程度;统计由于痰液堵塞、管道内积水等所引起湿化相关的呼吸机报警次数;统计呼吸机相关性肺炎发生率、机械通气时间、死亡率。结果 MR850组气管插管/切开处吸入气体温度为(36.97±1.57)℃,相对湿度为(98.35±1.32)%,绝对湿度为(43.66±1.15)mg H2O/L,与MR410组比较更接近人体最佳输入气体。MR850组气道分泌物更稀薄,管道积水更少,呼吸机报警次数更少,机械通气时间更短。结论与MR410湿化系统比较,MR850在机械通气治疗过程中更能够提供最佳的人工气道湿化,临床效果更好。Objective To compare the humidification effect of the MR410 humidification system and MR850 humidification system in the process of mechanical ventilation. Methods Sixty-nine patients underwent mechanical ventilation were recruited and randomly assigned to a MR850 group and a MR410 group. The temperature and relative humidity at sites where tracheal intubation or incision, the absolute humidity, the sticky degree of sputum in initial three days after admission were measured. Meanwhile the number of ventilator alarms related to sputum clogging and pipeline water, incidence of ventilator associated pneumonia,duration of mechanical ventilation,and mortality were recorded. Results In the MR850 group, the temperature of inhaled gas was （ 36.97 ± 1.57 ） ℃, relative humidity was （98.35 ± 1.32 ） %, absolute humidity was （43.66 ±1.15 ）mg H2 O/L, which were more closer to the optimal inhaled gas for human body. The MR850 humidification system was superior to the MR410 humidification system with thinner airway secretions, less pipeline water, fewer ventilator alarms, and shorter duration of mechanical ventilation. There was no significant difference in mortality between two groups. Conclusions Compared with MR410 humidification system, MR850 humidification system is more able to provide better artificial airway humidification and better clinical effect.

关 键 词：气道湿化 MR850 机械通气 呼吸机相关性肺炎 

分 类 号：R459.6[医药卫生—治疗学]