125例化学药品不良反应报告分析  

125 cases analysis with adverse drug reaction of chemical drugs

作　　者：李红[1,2] 乔逸[1] 王婧雯[1] 王磊[1] 常瑛[1] 文爱东[1] 

机构地区：[1]第四军医大学西京医院药剂科,西安710033 [2]西电集团医院药剂科,西安710077

出　　处：《西北药学杂志》2012年第5期482-484,共3页Northwest Pharmaceutical Journal

摘　　要：目的探寻我院近期化学药品不良反应发生的特点和规律,为临床安全、合理用药提供参考。方法对我院2011年1月-2011年9月上报的125例化学药品不良反应报告进行统计分析。结果 125例不良反应报告中涉及71种药物,抗感染药物居首位(76例,53.90%);以静脉滴注(70例,49.65%)和口服(61例,43.26%)给药为主;不良反应以皮肤及附件损害最为常见(60例,40.82%)。结论临床应合理使用抗感染药物尤其是三代头孢菌素类药物,重视不良反应监测,以降低不良反应的发生率。Objective To study the adverse drug reaction （ADR） characteristics and the regularity of chemical drugs in our hospital for the clinical safety and reasonable medication. Methods 125 ADR of chemical drugs cases collected from January of 2011 to Sep-tember of 2011 in our hospital were analyzed statistically, Results 125 ADR cases refered to 71 kinds of drugs,of which anti-infec-tive agents occupied the first place which had 76 cases （53.90%）. The majority of administration route was oral or vein,which had 70 cases （49.65%） and 61 cases （43.26%） ,respectively. The majority of ADR was skin destruction,which had 60 cases （40. 82% ）. Conclusion Great attention should be paid to the rational use of anti-infective agents, especially to the third generation cephalospo-rin to reduce the incidence rate of ADR.

关 键 词：药品不良反应 三代头孢菌素 统计分析 

分 类 号：R969.3[医药卫生—药理学]