2型糖尿病病人治疗前后血清中NO和葡萄糖浓度观察  

The Change of NO and Glucose Concentration in Serum Before and After Treatment for Patient with NIDDM

作　　者：陈淑芬[1] 王志华 苏寒冰[2] 余蓉[3] 陈大义[3] 

机构地区：[1]四川省中医药研究所附院检验科,四川成都610041 [2]成都市第一人民医院中心实验室,四川成都610016 [3]四川省卫生管理干部学院检验系,四川成都610041

出　　处：《四川省卫生管理干部学院学报》2000年第1期17-17,33,共2页Journal of Sichuan Continuing Education College of Medical Sciences

摘　　要：目的 :了解 2型糖尿病病人治疗前后血清中NO的变化 ,探讨NO做为糖尿病诊断和疗效观察指标的意义。方法 :血清NO测定采用改良Griess法 ,血糖测定采用葡萄糖氧化酶法。结果 :2型糖尿病病人治疗前血清中NO和葡萄糖浓度均高于对照组 (P <0 0 1 ) ,NO水平与葡萄糖浓度呈正相关 ,治疗后当血糖趋于正常时 ,血清中NO与正常人血清中NO无显著性差异 (P >0 0 5 )。结论 :NO与 2型糖尿病的发生和发展有关 ,测定血清NO水平可了解 2型糖尿病病人的病情 。Objective:To observe the change of NO and glucose concentration in serum before and after treatment for the patients with non insulin dependent diabetes(NIDDM) and discuss the significance of NO as an index for diagnoses and treatment of diabetes.Method:NO and glucose were determined with improved Griess method and GOD POD enzyme method respectively.Results:The concentration of NO and glucose in serum of patients were higher than these in control group.And the level of NO was correlated with the concentration of glucose.After the patients were treated,there is no significant difference for NO level between NIDDM group and control one.Conclusion:The level of NO is related with the generation and development of NIDDM.Its variation is helpful to judge and evaluate the results of treatment.

关 键 词：糖尿病 后氧化氮 葡萄糖 治疗 血清 

分 类 号：R587.105[医药卫生—内分泌]