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机构地区:[1]江苏省扬州五台山医院,江苏扬州225003 [2]江苏省荣军医院,江苏无锡214035
出 处:《实用临床医药杂志》2012年第14期99-102,共4页Journal of Clinical Medicine in Practice
摘 要:目的调查分析扬州、无锡两地区老年失眠患者门诊药物使用情况,对苯二氮卓类(BZD)等药物使用提出健康教育指导意见。方法采用自编调查表调查江苏省扬州五台山医院及江苏省荣军医院2009年11月~2010年3月因失眠而在门诊就诊的老年患者1224例,根据限定日剂量(DDD)和药物利用指数(DUI)对BZD等药物的临床使用进行分析。结果因失眠而就诊的老年人BZD使用频率高达91.83%;BZD合并抗精神病药物及抗抑郁药物占64.22%;两种以上BZD合并使用者占26.72%;艾司唑仑、阿普唑仑、氯硝西泮、硝西泮、地西泮的DUI〉1。结论扬州、无锡两地区老年人BZD等药物临床使用不尽合理,老年人BZD依赖情况严重,合并用药较多,通过健康教育指导等方法改变BZD等药物使用模式迫在眉睫。Objective To investigate the outpatient medication of elderly patients with insomnia in Yangzhou and Wuxi,and put forward guide of health education for use of benzodiazepine(BZD).Methods A self-designed questionnaire was used to investigate 1224 elderly patients who visited hospital because of insomnia.These patients were recruited from Yangzhou Wutaishan Hospital and Rongjun Hospital from November 2009 to March 2010.According to defined daily doses(DDD) and drug use index(DUI),clinical use of drugs such as BZD was analyzed.Results The BZD usage frequency was up to 91.83% in elderly patients who visited hospital due to insomnia.BZD combined with antipsychotic drug and antidepressant drug accounted for 64.22%.Combined use of two or more BZD constituted 26.72%.The DUI of estazolam,alprazolam,clonazepam,nitrazepam and diazepam was greater than 1.Conclusion The clinical use of BZD is unreasonable among elderly people in Yangzhou and Wuxi,who have serious dependence and more combined medication.Therefore,it is urgent to change the usage patterns of BZD through guide of health education.
关 键 词:苯二氮卓类药物(BZD) 限定日剂量(DDD) 药物使用指数(DUI) 失眠 健康教育
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