儿童Perthes病患者82例血液状态分析  

Analysis of blood condition of 82 children with Perthes disease

作　　者：林刚[1] 郑朋飞[1] 鞠黎[1] 董展[1] 楼跃[1] 

机构地区：[1]南京医科大学附属南京儿童医院,江苏南京210008

出　　处：《实用临床医药杂志》2012年第15期151-153,共3页Journal of Clinical Medicine in Practice

摘　　要：目的检测儿童Perthes病患者血脂代谢、凝血常规有无异常,以探讨血脂代谢和凝血功能障碍是否是Perthes病的病因。方法对82例儿童Perthes病患者(观察组)的凝血常规及血脂相关指标进行统计分析,并与120例非Perthes病患者(对照组)进行比较。结果观察组血脂指标中三酰甘油(TG)、总胆固醇(TC),高密度胆固醇(HDL-c)异常率和平均值与对照组比较均无明显差异(P>0.05);观察组活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(Fbg)、凝血酶原时间(PT)、国际标准化值(INR)异常率和平均值与对照组比较均无明显差异(P>0.05)。结论儿童Perthes病患者可能并不存在血脂代谢紊乱和血液的高凝低纤溶状态,血脂代谢和凝血功能障碍并不是Perthes病的病因。Objective To discuss whether the disorder of lipid metabolism or coagulation function is the cause of children′s Perthes disease.Methods We examined the TG,TC,HDL-c,APTT,TT,Fbg,PT and INR of 82 children with Perthes disease and compared the outcomes with children in the normal group（n=120）.Results There was no difference about the lipid metabolism（TG,TC,HDL-c） between the Perthes group and the control group（P〉0.05）.APTT,TT,Fbg,PT and INR showed no significant differences when compared with the control group（P〉0.05）.Conclusion In our study,the lipid metabolism and the coagulation function are not correlated with Perthes disease.

关 键 词：儿童 PERTHES病 血脂代谢 高凝状态 易栓假说 

分 类 号：R729[医药卫生—儿科]