3%的高渗盐水联合肾上腺素治疗毛细支气管炎的临床研究  

Clinical study on 3% hypertonic saline combined with epinephrine through atomizing inhalation to treat bronchiolitis

作　　者：顾冬云[1] 陈志宏[1] 陈沛文[1] 

机构地区：[1]江苏省靖江市人民医院儿科,江苏靖江214500

出　　处：《实用临床医药杂志》2012年第15期156-157,共2页Journal of Clinical Medicine in Practice

摘　　要：目的观察3%高渗盐水(HS)联合小剂量肾上腺素雾化吸入治疗毛细支气管炎的效果。方法选择109例毛细支气管炎住院治疗的患儿,随机分为对照组与治疗组。治疗组用小剂量肾上腺素溶于HS进行雾化吸入治疗,对照组用万托林溶于0.9%生理盐水(NS)中雾化吸入治疗。比较2组患儿临床症状改善情况、住院天数及治疗前后患儿的肺功能。结果治疗后2组临床症状、体征均明显改善;治疗组改善更明显,平均住院日更短、肺功能改善更优。结论 HS联合小剂量肾上腺素吸入治疗毛细支气管炎疗效更显著。Objective To explore the clinical effect of the 3% hypertonic saline combined with inhalation of low doses of epinephrine on bronchiolitis in infants.Methods A total of 109 infants with bronchiolitis in our hospital were randomly divided into treatment group and control group.The treatment group was treated by using epinephrine to dissolve in 3% hypertonic saline as inhalation therapy,and the control group by using salbutamol sulphate aerosol to dissolve in 0.9% saline as inhalation therapy.The symptom improvement,duration of hospitalization and changes in pulmonary function in the two groups before and after treatment were compared.Results After treatment,clinical symptoms and signs improved in the two groups,improvement in the treatment group being more significant,with shorter average hospital stay and better improvement in the average lung functions compared with the control group.Conclusion The 3% hypertonic saline combined with low doses of epinephrine inhalation has a therapeutic effect in the treatment of bronchiolitis.

关 键 词：毛细支气管炎3%高渗盐水 肾上腺素 万托林 

分 类 号：R562.2[医药卫生—呼吸系统]