枳椇子乙酸乙酯部位化学成分的研究  

Studies on the Chemical Constituents from Hovenia Acerba Lindl Extracted with the Ethyl Acetate Parts

作　　者：谢蓉蓉[1] 张德志[1] 庞小雄[1] 李欢[1] 

机构地区：[1]广东药学院天然药物化学教研室,广东广州510006

出　　处：《亚太传统医药》2012年第9期27-28,共2页Asia-Pacific Traditional Medicine

摘　　要：目的:分离鼠李科植物枳椇子种子乙酸乙酯部位的化学成分。方法:运用柱色谱法对枳椇子乙酸乙酯部位进行分离,并根据理化性质及波谱数据对所分离的化合物进行结构鉴定。结果:从中分离得到3个化合物,鉴定为:hovenitinsⅠ(Ⅰ),laricetrin(Ⅱ),Dihydromyricetin(Ⅲ)。结论:乙酸乙酯部位是枳椇子解酒的活性提取部位,该化学成分研究分离得到的三个化合物均为黄酮类,为新药的研发提供了科学依据。Objective：To investigate the chemical constituents from Hovenia acerba Lindl ethyl acetate extract. Methods：Repeat- ed silica gel chromatographies were employed for the isolation. IR,MS and NMR were used to elucidate their structures. Results： Three compounds were obtained and identified as hovenitinshovenitins I （ Ⅰ ）, laricetrin（ Ⅱ ）, Dihydromyricetin （Ⅲ ）. Conclusion ： Ethyl ace- tate parts is the active extracted parts of hepatoprotective thunb fruit for wine,the chemical composition can provide certain scientific basis of the research and development of new drug.

关 键 词：枳椇子 化学成分 乙酸乙酯部位 

分 类 号：R284.1[医药卫生—中药学]