妊娠期肾病综合征与重度子痫前期的相关分析  

Correlation analysis of nephritic syndrome of pregnancy and severe preeclampsia

作　　者：金丰梅[1] 安莉莉[1] 

机构地区：[1]广东省珠海市妇幼保健院珠海市重症孕产妇救治中心,广东珠海519000

出　　处：《河北联合大学学报（医学版）》2012年第5期618-620,共3页Journal of North China Coal Medical College

摘　　要：①目的探讨重度子痫前期并发妊娠期肾病综合征(NSP)的临床特点、母婴影响以及强的松治疗的疗效。②方法回顾性分析我院148例重度子痫前期病例的临床资料,其中36例合并肾病综合征为肾病组,其余未并发NSP的112例为对照组,分析两组母婴并发症。NSP组中应用强的松治疗17例(强的松治疗组),常规治疗19例(对照治疗组),比较不同治疗下的母婴并发症的发生情况。③结果NSP组终止妊娠孕周明显少于对照组(P<0.05);NSP组腹水发生率、胎盘早剥、肾功能异常的发生率明显高于对照组(P<0.05);NSP组围生儿并发症的发生率明显高于对照组(P<0.05);强的松治疗组终止妊娠周数明显延长,肾功能损害、胎盘早剥、凝血功能异常和产后出血的发生率明显减少(P<0.05);新生儿并发症的发生率明显降低(P<0.05)。④结论 NSP是重度子痫前期的特殊类型,对母婴影响较大,在积极治疗的同时,应用强的松治疗可以改善围生儿预后,同时也可以改善孕妇的肾脏功能。Objective To explore the clinical features of nephritic syndrome of pregnancy（NSP）induced severe preeclampsia the impact of maternity-infant,and the curative effect of prednisone.Methods 148 cases of severe preeclampsia,36 cases of NS-PIH（NSP group）,112 cases of severe preeclampsia（control group）had been reviewed,analysis maternity-infant complication.17 cases of prednisone application（prednisone treatment group） and 19 cases of routine treatment（control group）,compare the maternity-infant complications of different treatments.Results The termination of pregnancy gestational weeks in NSP group is less than control group（P0.05）;The incidence rate of ascites,placental abruption,abnormal renal function in NSP group is higher than control group（P0.05）.The incidence rate of perinatal complications in NSP group is higher than control group（P0.05）.Prednisone treatment group is to extend termination of pregnancy gestational weeks obviously,and to reduce the renal damage,placental abruption,disfunction of blood clotting,postpartum hemorrhage obviously（P0.05）.The incidence rate of neonatal complications is also lower than prednisone treatment group,the difference was statistically significant（P0.05）.Conclusion NSP is the special type of severe preeclampsia,and has great impact on maternity-infant influence.At the same time of active treatment,the prednisone application could improve the perinatal prognosis and the renal function in pregnant women.

关 键 词：妊娠期肾病综合征 子痫前期重度 并发症 强的松 

分 类 号：R714.25[医药卫生—妇产科学]