PⅢ改性ePTFE膜对细菌生存状态的影响研究  

Surface Modification of Expanded Polytetrafluoroethylene Membrane by Oxygen Plasma Immersion Ion Implantation and its Survival Condition

作　　者：吴艳[1] 米方林[1] 张玉梅 王勤涛 

机构地区：[1]川北医学院口腔科,四川南充637000 [2]第四军医大学口腔医院,陕西西安710032

出　　处：《现代生物医学进展》2012年第24期4647-4650,共4页Progress in Modern Biomedicine

摘　　要：目的:探讨等离子注入技术(Plasma immersion ion implantation,PIII)对膨体聚四氟乙烯(ePTFE)膜改性后表面性能以及对细菌生存状态的影响。方法:采用氧等离子注入技术(PⅢ)对ePTFE膜表面处理,获得改性ePTFE膜,利用扫描电镜(SEM)观察改性ePTFE膜和未处理膜的表面形貌,体外培养变形链球菌,观察改性前后各组膜作体外细菌生存状态变化。结果:与未处理ePTFE膜相比,改性ePTFE膜表面形貌、亲水性发生改变。荧光染色后观察长脉冲组表面的细菌最少;短脉冲组膜表面粘附的细菌密集,形成生物膜;空白组可见少量死菌和活菌粘附于ePTFE膜上。结论:长脉冲PⅢ改性ePTFE膜后有良好的抗细菌粘附能力。Objective： The study aimed at the surface modification of oral biomaterials（expanded polytetrafluoro-ethylene, ePTFE） by means of oxygen plasma immersion ion implantation （PIII） and evaluating its survival condition. Methods： Pill had been used to modify the surface of ePTFE membrane, and the modified ePTFE samples were investigtaied by scanning electron microseopy（SEM）. Its survival condition to the modified ePTFE was studied. Results： It revealed that Pill changed surface morphology and water contact angle of ePTFE. The bacteria survival condition indicated that after fluorescence-labeling, less bacteria in long pulse Pill ePTFE, and more bacte- ria in short pulse Pill ePTFE and virgin sainples. Conclusion： It manifested that long pulse Pill treated ePTFE significantly reduced the bacterial adhesion in vitro.

关 键 词：等离子浸没离子注入(PIII) 膨体聚四氟乙烯 生物膜 

分 类 号：Q73[生物学—分子生物学]