抗菌药物在新生儿病房中的应用  

Application of antibiotics in neonatal wards

作　　者：朱进秋[1] 沈宁[2] 王煜[3] 罗维真[1] 付燕[4] 张静[1] 

机构地区：[1]昆明市妇幼保健院新生儿科,云南昆明650031 [2]昆明市妇幼保健院病案室,云南昆明650031 [3]昆明市妇幼保健院感染控制科,云南昆明650031 [4]昆明市妇幼保健院药剂科,云南昆明650031

出　　处：《中华医院感染学杂志》2012年第17期3836-3837,3840,共3页Chinese Journal of Nosocomiology

摘　　要：目的分析新生儿病房抗菌药物使用情况,为降低新生儿抗菌药物使用率提供依据。方法对医院2003-2010年新生儿病房的抗菌药物使用情况进行分析,前4年设为对照组,后4年设为试验组,对两组新生儿抗菌药物使用率、医院感染发生率、治愈好转率、平均住院日,进行统计学处理及分析。结果试验组抗菌药物使用率较对照组下降50.28%,差异有统计学意义(P<0.01);两组医院感染发生率经统计学处理差异无统计学意义;治愈好转率试验组为99.04%,对照组为97.19%,较前提高;平均住院日试验组平均8.58d,对照组平均9.23d,较前减少,差异均有统计学意义(P<0.01)。结论新生儿病房内降低抗菌药物的使用率,并未使医院感染率、平均住院日增加,治愈好转率也未降低。OBJECTIVE To investigate the application of antibiotics in neonatal wards so as to provide basis for decreasing the utilization rate of antibiotics for the neonates.METHODS The application of antibiotics in the neonatal wards from 2003 to 2010 was analyzed,the application during the first four years was set as the control group,the application of the later four years was set as the test group;the utilization rate of antibiotics,the rate of nosocomial infections,cure rate,and the average hospital stay of the two groups of neonates were statistically processed and analyzed.RESULTS As compared with the control group,the utilization rate of the test group decreased by 50.28%,the difference was statistically significant（P〈0.01）;the difference in the incidence rate of nosocomial infections was not statistically significant after the statistical analysis;the cure rate of the test group was 99.04%,97.19% of control group;the average hospital stay of the test group was 8.58 d,9.23 d of the control group,the differences were statistically significant（P〈0.01）.CONCLUSION To decrease the utilization rate of antibiotics in the neonatal ward does not play any role in increasing the rate of nosocomial infections and the average hospital stay as well as reducing the cure rate.

关 键 词：新生儿病房 抗菌药物 使用率 医院感染率 平均住院日 

分 类 号：R978.1[医药卫生—药品]